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  • 1
    Article
    Article
    1983
    ISSN: 0001-3374 
    In: Absatzwirtschaft, 1983(6), p.48
    ISSN: 0001-3374
    Source: wiso Fachzeitschriften (GBI-Genios Deutsche Wirtschaftsdatenbank GmbH) 〈img src="http://exlibris-pub.s3.amazonaws.com/wiso_logo.jpg" style="vertical-align:middle;margin-left:7px"〉
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  • 2
    Language: English
    In: The Journal of Physical Chemistry C, 08/13/2015, Vol.119(32), pp.18278-18286
    Description: The disinfection of bacteria by thermally excited pyroelectric materials in aqueous environments provides opportunities for the development of new means of sanitization. However, little is known about the formation of reactive oxygen species (ROS) at the surface of the thermally excited pyroelectric materials. To investigate the pyroelectrically driven ROS generation we performed OH radical specific measurements of thermally stimulated barium titanate nanoparticles in contact with palladium nanoparticles. Through electron spin resonance measurements with the spin trap BMPO (5-tert-butoxycarbonyl 5-methyl-1-pyrroline n-oxide) and fluorescence spectroscopy of 7-hydroxycoumarin, OH radical generation was detected, which confirms the hypothesis of pyroelectric ROS production. Since pyroelectric potential changes are insufficient for direct electrochemical OH radical generation, we propose a two-step charge-transfer model facilitated by intermittent contact between the palladium and the pyroelectric nanopartic...
    Subject(s): Chemistry;
    ISSN: 1932-7447
    E-ISSN: 1932-7455
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  • 3
    Language: English
    In: Diabetes, November 2011, Vol.60(11), pp.2954-62
    Description: To assess the potential role of FoxP3-expressing regulatory T cells (Tregs) in reversing obesity-linked insulin resistance and diabetic nephropathy in rodent models and humans. To characterize the role of Tregs in insulin resistance, human visceral adipose tissue was first evaluated for Treg infiltration and second, the db/db mouse model was evaluated. Obese patients with insulin resistance displayed significantly decreased natural Tregs but an increase in adaptive Tregs in their visceral adipose tissue as compared with lean control subjects. To further evaluate the pathogenic role of Tregs in insulin resistance, the db/db mouse model was used. Treg depletion using an anti-CD25 monoclonal antibody enhanced insulin resistance as shown by increased fasting blood glucose levels as well as an impaired insulin sensitivity. Moreover, Treg-depleted db/db mice developed increased signs of diabetic nephropathy, such as albuminuria and glomerular hyperfiltration. This was paralleled by a proinflammatory milieu in both murine visceral adipose tissue and the kidney. Conversely, adoptive transfer of CD4(+)FoxP3(+) Tregs significantly improved insulin sensitivity and diabetic nephropathy. Accordingly, there was increased mRNA expression of FoxP3 as well as less abundant proinflammatory CD8(+)CD69(+) T cells in visceral adipose tissue and kidneys of... Data suggest a potential therapeutic value of Tregs to improve insulin resistance and end organ damage in type 2 diabetes by limiting the proinflammatory milieu.
    Subject(s): Insulin Resistance ; Diabetic Nephropathies -- Immunology ; Obesity -- Immunology ; T-Lymphocytes, Regulatory -- Immunology
    ISSN: 0012-1797
    E-ISSN: 1939-327X
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  • 4
    Language: English
    In: Wiener Medizinische Wochenschrift, 2014, Vol.164(5), pp.109-119
    Description: ALTERNATE is an international observational study evaluating biweekly darbepoetin alfa (DA) in adult dialysis patients in clinical practice. Austrian ALTERNATE results are presented here ( n  = 505). The follow-up study ALTERNATE follow-up (AFU) followed Austrian ALTERNATE patients for an additional 12 months ( n  = 135). Data were collected 6 months before and 12 months after conversion to biweekly dosing and during 12 months of follow-up. The primary measures were hemoglobin concentration 12 months after conversion and at the end of AFU, respectively. Mean (95 % CI) hemoglobin (g/dL) was 11.87 (11.75–11.99) at conversion, 11.71 (11.58–11.83) at month 12, and 11.66 (11.45–11.86) at end of AFU. Geometric mean (95 % CI) weekly dose (μg/wk) was 32.97 (30.80–35.30) at conversion, 29.90 (26.71–33.46) 12 months after conversion, and 24.38 (18.40–30.35) at end of AFU. The studies show that hemoglobin and dose could be effectively maintained over an extended period of time after conversion from higher frequency erythropoiesis-stimulating agents to biweekly DA. ALTERNATE ist eine internationale Beobachtungsstudie, welche die zweiwöchentliche Gabe von Darbepoetin alfa (DA) bei erwachsenen Dialysepatienten in der klinischen Praxis untersuchte. Die österreichische Auswertung wird hier vorgestellt ( = 505). Die Nachbeobachtungsstudie AFU, dokumentierte österreichische ALTERNATE Patienten über weitere 12 Monate ( = 135). Daten wurden sechs Monate vor und 12 Monate nach Umstellung auf das zweiwöchentliche Verabreichungsintervall, sowie innerhalb einer 12-monatigen Nachbeobachtung gesammelt. Die primären Messparameter waren die Hämoglobinwerte 12 Monate nach Umstellung und am Ende von AFU. Der mittlere Hämoglobinwert (95 % CI; g/dl) war 11,87 (11,75–11,99) bei Umstellung, 11,71 (11,58–11,83) zu Monat 12 und 11,66 (11,45–11,86) am Ende von AFU. Die geometrisch mittlere Wochendosis (95 % CI; µg/Woche) war 32,97 (30,80–35,30) bei Umstellung, 29,90 (26,71–33,46) 12 Monate nach Umstellung und 24,38 (18,40–30,35) am Ende von AFU. Die Studien zeigen, dass der Hämoglobinspiegel und die Dosis nach Umstellung von einem höherfrequenten erythropoese-stimulierenden Faktor auf zweiwöchentliches DA über eine längeren Zeitraum stabil gehalten werden konnten.
    Subject(s): Anemia ; Darbepoetin alfa ; Chronic kidney disease ; Hemoglobin ; Observational study
    ISSN: 0043-5341
    E-ISSN: 1563-258X
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  • 5
    In: Ecohydrology, October 2014, Vol.7(5), pp.1378-1391
    Description: In the literature, contrasting effects of plant species richness on the soil water balance are reported. Our objective was to assess the effects of plant species and functional richness and functional identity on soil water contents and water fluxes in the experimental grassland of the Jena Experiment. The Jena Experiment comprises 86 plots on which plant species richness (0, 1, 2, 4, 8, 16, and 60) and functional group composition (zero to four functional groups: legumes, grasses, tall herbs, and small herbs) were manipulated in a factorial design. We recorded meteorological data and soil water contents of the 0·0–0·3 and 0·3–0·7 m soil layers and calculated actual evapotranspiration (), downward flux (), and capillary rise with a soil water balance model for the period 2003–2007. Missing water contents were estimated with a Bayesian hierarchical model. Species richness decreased water contents in subsoil during wet soil conditions. Presence of tall herbs increased soil water contents in topsoil during dry conditions and decreased soil water contents in subsoil during wet conditions. Presence of grasses generally decreased water contents in topsoil, particularly during dry phases; increased and decreased from topsoil; and decreased from subsoil. Presence of legumes, in contrast, decreased and increased from topsoil and increased from subsoil. Species richness probably resulted in complementary water use. Specific functional groups likely affected the water balance via specific root traits (e.g. shallow dense roots of grasses and deep taproots of tall herbs) or specific shading intensity caused by functional group effects on vegetation cover. Copyright © 2013 John Wiley & Sons, Ltd.
    Subject(s): The Jena Experiment ; Biodiversity ; Plant Diversity ; Water Content ; Evapotranspiration ; Soil Water Flux
    ISSN: 1936-0584
    E-ISSN: 1936-0592
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  • 6
    Language: English
    In: PloS one, 13 October 2010, Vol.5(10), pp.e13382
    Description: The diversity-stability hypothesis states that current losses of biodiversity can impair the ability of an ecosystem to dampen the effect of environmental perturbations on its functioning. Using data from a long-term and comprehensive biodiversity experiment, we quantified the temporal stability of 42 variables characterizing twelve ecological functions in managed grassland plots varying in plant species richness. We demonstrate that diversity increases stability i) across trophic levels (producer, consumer), ii) at both the system (community, ecosystem) and the component levels (population, functional group, phylogenetic clade), and iii) primarily for aboveground rather than belowground processes. Temporal synchronization across studied variables was mostly unaffected with increasing species richness. This study provides the strongest empirical support so far that diversity promotes stability across different ecological functions and levels of ecosystem organization in grasslands.
    Subject(s): Ecosystem ; Poaceae -- Physiology
    ISSN: 1932-6203
    E-ISSN: 1932-6203
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  • 7
    Language: English
    In: PLoS ONE, 13 October 2010
    Description: The diversity–stability hypothesis states that current losses of biodiversity can impair the ability of an ecosystem to dampen the effect of environmental perturbations on its functioning. Using data from a long-term and comprehensive biodiversity experiment, we quantified the temporal stability of 42 variables characterizing twelve ecological functions in managed grassland plots varying in plant species richness. We demonstrate that diversity increases stability i) across trophic levels (producer, consumer), ii) at both the system (community, ecosystem) and the component levels (population, functional group, phylogenetic clade), and iii) primarily for aboveground rather than belowground processes. Temporal synchronization across studied variables was mostly unaffected with increasing species richness. This study provides the strongest empirical support so far that diversity promotes stability across different ecological functions and levels of ecosystem organization in grasslands.
    Subject(s): Sciences (General)
    ISSN: 1932-6203
    E-ISSN: 1932-6203
    Source: Research Collection (ETH Zurich)
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  • 8
    Language: English
    Description: This data set contains measurements of dissolved phosphorus (total dissolved nitrogen: TDP, dissolved inorganic phosphorus: PO4P and dissolved organic phosphorus: DOP) in samples of soil water collected in 2002 from the main experiment plots of a large grassland biodiversity experiment (the Jena Experiment; see further details below). In the main experiment, 82 grassland plots of 20 x 20 m were established from a pool of 60 species belonging to four functional groups (grasses, legumes, tall and small herbs). In May 2002, varying numbers of plant species from this species pool were sown into the plots to create a gradient of plant species richness (1, 2, 4, 8, 16 and 60 species) and functional richness (1, 2, 3, 4 functional groups). Plots were maintained by bi-annual weeding and mowing. Glass suction plates with a diameter of 12 cm, 1 cm thickness and a pore size of 1–1.6 µm (UMS GmbH, Munich, Germany) were installed in April 2002 in depths of 10, 20, 30 and 60 cm to collect...
    Subject(s): Date/Time End ; Date/Time Start ; Depth, Soil ; Depth, Soil, Maximum ; Depth, Soil, Minimum ; Exp ; Experiment ; Experimental Plot ; Jena Experiment 2002 ; Jenexp ; Jenexp_2002 ; Phosphorus, Inorganic, Dissolved ; Phosphorus, Organic, Dissolved ; Phosphorus, Total Dissolved ; The Jena Experiment ; Thuringia, Germany ; Treatment: Aboveground: Pesticide ; Treatment: Below Pesticide ; Treatment: Drought ; Treatment: Eartworm Exclosure
    Source: PANGAEA: Publishing Network for Geoscientific & Environmental Data
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  • 9
    Language: English
    Description: This data set contains measurements of dissolved phosphorus (total dissolved nitrogen: TDP, dissolved inorganic phosphorus: PO4P and dissolved organic phosphorus: DOP) in samples of soil water collected in 2003 from the main experiment plots of a large grassland biodiversity experiment (the Jena Experiment; see further details below). In the main experiment, 82 grassland plots of 20 x 20 m were established from a pool of 60 species belonging to four functional groups (grasses, legumes, tall and small herbs). In May 2002, varying numbers of plant species from this species pool were sown into the plots to create a gradient of plant species richness (1, 2, 4, 8, 16 and 60 species) and functional richness (1, 2, 3, 4 functional groups). Plots were maintained by bi-annual weeding and mowing. Glass suction plates with a diameter of 12 cm, 1 cm thickness and a pore size of 1–1.6 mm (UMS GmbH, Munich, Germany) were installed in April 2002 in depths of 10, 20, 30 and 60 cm to collect...
    Subject(s): Date/Time End ; Date/Time Start ; Depth, Soil ; Depth, Soil, Maximum ; Depth, Soil, Minimum ; Exp ; Experiment ; Experimental Plot ; Jena Experiment 2003 ; Jenexp ; Jenexp_2003 ; Phosphorus, Inorganic, Dissolved ; Phosphorus, Organic, Dissolved ; Phosphorus, Total Dissolved ; The Jena Experiment ; Thuringia, Germany ; Treatment: Aboveground: Pesticide ; Treatment: Below Pesticide ; Treatment: Drought ; Treatment: Eartworm Exclosure
    Source: PANGAEA: Publishing Network for Geoscientific & Environmental Data
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  • 10
    Language: English
    Description: This data set contains measurements of dissolved phosphorus (total dissolved nitrogen: TDP, dissolved inorganic phosphorus: PO4P and dissolved organic phosphorus: DOP) in samples of soil water collected in 2004 from the main experiment plots of a large grassland biodiversity experiment (the Jena Experiment; see further details below). In the main experiment, 82 grassland plots of 20 x 20 m were established from a pool of 60 species belonging to four functional groups (grasses, legumes, tall and small herbs). In May 2002, varying numbers of plant species from this species pool were sown into the plots to create a gradient of plant species richness (1, 2, 4, 8, 16 and 60 species) and functional richness (1, 2, 3, 4 functional groups). Plots were maintained by bi-annual weeding and mowing. Glass suction plates with a diameter of 12 cm, 1 cm thickness and a pore size of 1–1.6 µm (UMS GmbH, Munich, Germany) were installed in April 2002 in depths of 10, 20, 30 and 60 cm to collect...
    Subject(s): Date/Time End ; Date/Time Start ; Depth, Soil ; Depth, Soil, Maximum ; Depth, Soil, Minimum ; Exp ; Experiment ; Experimental Plot ; Jena Experiment 2004 ; Jenexp ; Jenexp_2004 ; Phosphorus, Inorganic, Dissolved ; Phosphorus, Organic, Dissolved ; Phosphorus, Total Dissolved ; The Jena Experiment ; Thuringia, Germany ; Treatment: Aboveground: Pesticide ; Treatment: Below Pesticide ; Treatment: Drought ; Treatment: Eartworm Exclosure
    Source: PANGAEA: Publishing Network for Geoscientific & Environmental Data
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