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  • 1
    Language: English
    In: Computer Science in Economics and Management, 1992, Vol.5(3), pp.183-220
    Description: Two algorithms, and corresponding Fortran computer programs, for the computation of posterior moments and densities using the principle of importance sampling are described in detail. The first algorithm makes use of a multivariate Student t importance function as approximation of the posterior. It can be applied when the integrand is moderately skew. The second algorithm makes use of a decomposition: a multivariate normal importance function is used to generate directions (lines) and one-dimensional classical quadrature is used to evaluate the integrals defined on the generated lines. The second algorithm can be used in cases where the integrand is possibly very skew in any direction.
    Subject(s): Bayesian analysis ; Monte Carlo integration ; importance sampling
    ISSN: 0921-2736
    E-ISSN: 1572-9974
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  • 2
    In: Journal of the Royal Statistical Society: Series D (The Statistician), June 1987, Vol.36(2-3), pp.83-90
    Description: In earlier work (van Dijk, 1984, Chapter 3) one of the authors discussed the use of Monte Carlo integration methods for the computation of the multivariate integrals that are defined in the posterior moments and densities of the parameters of interest of econometric models. In the present paper we describe the computational steps of one Monte Carlo method, which is known in the literature as importance sampling. Further, a set of standard programs is available, which may be used for the implementation of a simple case of importance sampling. The computer programs have been written in FORTRAN 77.
    Subject(s): Statistics;
    ISSN: 0039-0526
    E-ISSN: 1467-9884
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  • 3
    Language: English
    In: Gerontology and Geriatric Medicine, 09 October 2015, Vol.1
    Description: Objective: To explore the value of day services at green care farms (GCFs) in terms of social participation for people with dementia. Method: Semi-structured interviews were conducted with people with dementia who attended day services at a GCF (GCF group, n = 21), were on a waiting list (WL) for day services at a GCF (WL group, n = 12), or attended day services in a regular day care facility (RDCF group, n = 17) and with their family caregivers. Results: People with dementia in the GCF and WL group were primarily males, with an average age of 71 and 76 years, respectively, who almost all had a spousal caregiver. People with dementia in the RDCF group were mostly females with an average age of 85 years, most of whom had a non-spousal caregiver. For both the GCF and RDCF groups, it was indicated that day services made people with dementia feel part of society. The most important domains of social participation addressed by RDCFs were social interactions and recreational activities....
    Subject(s): Adult Day Care ; Adult Day Services ; Civic Engagement ; Dementia ; Green Care Farms ; Social Participation ; Medicine
    E-ISSN: 2333-7214
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  • 4
    In: Mediators of Inflammation, 2013, Vol.2013, 6 pages
    Description: The aim of this study was to assess cross-sectional and longitudinal correlations between uEPX and other markers of asthma control and eosinophilic airway inflammation. . We measured uEPX at baseline, after 1 year and after 2 years in 205 atopic asthmatic children using inhaled fluticasone. At the same time points, we assessed symptom scores (2 weeks diary card), lung function (forced expiratory volume in one second (FEV)), airway hyperresponsiveness (AHR), and percentage eosinophils in induced sputum (% eos). . We found negative correlations between uEPX and FEV at baseline (), after 1 year () and after 2 years (). Within-patient changes of uEPX showed a negative association with FEV changes (at 1 year: ; at 2 years: ). Within-patient changes from baseline of uEPX correlated with changes in % eos. No relations were found between uEPX and symptoms. . In this population of children with atopic asthma, uEPX correlated with FEV and % eos, and within-subjects changes in uEPX correlated with changes in FEV and % eos. As the associations were weak and the scatter of uEPX wide, it seems unlikely that uEPX will be useful as a biomarker for monitoring asthma control in the individual child.
    Subject(s): Eosinophils – Health Aspects ; Childhood Asthma – Physiological Aspects ; Inflammation – Physiological Aspects;
    ISSN: 0962-9351
    E-ISSN: 1466-1861
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  • 5
    Article
    Article
    2015
    ISSN: 0028-0836 
    In: Nature, 2015, Vol.524(7566), p.507
    ISSN: 0028-0836
    E-ISSN: 14764687
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  • 6
    Article
    Article
    2011
    ISSN: 0028-0836 
    In: Nature, 2011, Vol.471(7338), p.310
    Subject(s): Animals–Metabolism ; Apoptosis–Genetics ; Casp8 and Fadd-Like Apoptosis Regulating Protein–Metabolism ; Caspase 8–Enzymology ; Cell Proliferation–Genetics ; Embryo Loss–Metabolism ; Embryo, Mammalian–Cytology ; Fas-Associated Death Domain Protein–Embryology ; Gtpase-Activating Proteins–Enzymology ; Humans–Metabolism ; Lymphocytes–Deficiency ; Mice–Genetics ; Necrosis–Metabolism ; Receptor-Interacting Protein Serine-Threonine Kinases–Deficiency ; Fas Receptor–Genetics ; Fas Receptor–Metabolism ; Fas Receptor–Cytology ; Fas Receptor–Immunology ; Fas Receptor–Genetics ; Fas Receptor–Deficiency ; Fas Receptor–Genetics ; Fas Receptor–Metabolism ; Fas Receptor–Metabolism ; Casp8 and Fadd-Like Apoptosis Regulating Protein ; Cflar Protein, Mouse ; Fadd Protein, Mouse ; Fas-Associated Death Domain Protein ; Gtpase-Activating Proteins ; Ralbp1 Protein, Mouse ; Fas Receptor ; Receptor-Interacting Protein Serine-Threonine Kinases ; Ripk3 Protein, Mouse ; Caspase 8;
    ISSN: 0028-0836
    E-ISSN: 14764687
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  • 7
    Article
    Article
    2016
    ISSN: 0036-8075 
    Language: English
    In: Science (New York, N.Y.), 26 August 2016, Vol.353(6302), pp.869-70
    Description: The atmosphere-ocean system interacts with the solid Earth to produce seismic signals called microseisms, which are observed globally. This interaction results from large-scale, slowly moving extratropical storms but also from smaller, intense weather systems such as tropical cyclones (called hurricanes in the Atlantic and eastern Pacific, and typhoons in the western Pacific). These are smaller storms, often travel much faster, and have steeper atmospheric pressure gradients that produce very strong winds. All storm systems generate various types of microseisms, which have been studied extensively. A special case of fast-developing, small, extratropical storms in which the central pressure intensifies rapidly, dropping by more than 1 mbar/hour for 24 hours, is called a "weather bomb" (1). On page 919 of this issue, Nishida and Takagi (2) report on the detection of previously unobserved S wave microseisms generated under a weather bomb between Greenland and...
    Subject(s): Cyclones ; Weather ; Microseisms ; Climatology ; Atmospheric Pressure ; Barometric Pressure ; Storms ; Earth Atmosphere ; Miscellaneous Sciences (So) ; (An);
    ISSN: 0036-8075
    E-ISSN: 1095-9203
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  • 8
    Article
    Article
    2011
    ISSN: 0028-0836 
    In: Nature, 2011, Vol.480(7376), p.229
    Description: Milankovitch proposed that Earth resides in an interglacial state when its spin axis both tilts to a high obliquity and precesses to align the Northern Hemisphere summer with Earth's nearest approach to the Sun. This general concept has been elaborated into hypotheses that precession, obliquity or combinations of both could pace deglaciations during the late Pleistocene. Earlier tests have shown that obliquity paces the late Pleistocene glacial cycles but have been inconclusive with regard to precession, whose shorter period of about 20,000 years makes phasing more sensitive to timing errors. No quantitative test has provided firm evidence for a dual effect. Here I show that both obliquity and precession pace late Pleistocene glacial cycles. Deficiencies in time control that have long stymied efforts to establish orbital effects on deglaciation are overcome using a new statistical test that focuses on maxima in orbital forcing. The results are fully consistent with Milankovitch's proposal but also admit the possibility that long Southern Hemisphere summers contribute to deglaciation.
    Subject(s): Sciences (General) ; Physics;
    ISSN: 0028-0836
    E-ISSN: 14764687
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  • 9
    Article
    Article
    2011
    ISSN: 0028-0836 
    In: Nature, 2011, Vol.472(7343), p.381
    ISSN: 0028-0836
    E-ISSN: 14764687
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  • 10
    Article
    Article
    2013
    ISSN: 0028-0836 
    In: Nature, 2013, Vol.495(7440), p.S12
    Subject(s): Aquatic Organisms–Metabolism ; Bacteria–Classification ; Biofilms–Genetics ; Cupriavidus–Isolation & Purification ; Gold–Metabolism ; Gold Compounds–Growth & Development ; Metal Nanoparticles–Drug Effects ; Microbiology–Metabolism ; Mining–Analysis ; Oxidation-Reduction–Economics ; Oxidation-Reduction–Isolation & Purification ; Oxidation-Reduction–Metabolism ; Oxidation-Reduction–Metabolism ; Oxidation-Reduction–Pharmacology ; Oxidation-Reduction–Economics ; Oxidation-Reduction–Microbiology ; Oxidation-Reduction–Economics ; Oxidation-Reduction–Trends ; Oxidation-Reduction–Methods ; Gold Compounds ; Gold Chloride ; Gold;
    ISSN: 0028-0836
    E-ISSN: 14764687
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