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  • 1
    Language: English
    In: Journal of experimental botany, 2013-01-01, Vol.64 (10), p.2653-2664
    Description: The metabolism of bromine in marine brown algae remains poorly understood. This contrasts with the recent finding that the accumulation of iodide in the brown alga Laminaria serves the provision of an inorganic antioxidant – the first case documented from a living system. The aim of this study was to use an interdisciplinary array of techniques to study the chemical speciation, transformation, and function of bromine in Laminaria and to investigate the link between bromine and iodine metabolism, in particular in the antioxidant context. First, bromine and iodine levels in different Laminaria tissues were compared by inductively coupled plasma MS. Using in vivo X-ray absorption spectroscopy, it was found that, similarly to iodine, bromine is predominantly present in this alga in the form of bromide, albeit at lower concentrations, and that it shows similar behaviour upon oxidative stress. However, from a thermodynamic and kinetic standpoint, supported by in vitro and reconstituted in vivo assays, bromide is less suitable than iodide as an antioxidant against most reactive oxygen species except superoxide, possibly explaining why kelps prefer to accumulate iodide. This constitutes the first-ever study exploring the potential antioxidant function of bromide in a living system and other potential physiological roles. Given the tissue-specific differences observed in the content and speciation of bromine, it is concluded that the bromide uptake mechanism is different from the vanadium iodoperoxidase-mediated uptake of iodide in L. digitata and that its function is likely to be complementary to the iodide antioxidant system for detoxifying superoxide.
    Subject(s): RESEARCH PAPER ; Fundamental and applied biological sciences. Psychology ; Biological and medical sciences ; Plant physiology and development ; Bromine - metabolism ; Kelp - chemistry ; Antioxidants - metabolism ; Iodine - metabolism ; Iodine - analysis ; Kelp - metabolism ; Kelp - genetics ; Laminaria - metabolism ; Iodide Peroxidase - metabolism ; Bromine - analysis ; Iodide Peroxidase - genetics ; Laminaria - chemistry ; Laminaria - genetics ; electron paramagnetic resonance ; reactive oxygen species ; Research Paper ; halocarbons ; X-ray absorption spectroscopy ; Antioxidant ; brown algae
    ISSN: 0022-0957
    E-ISSN: 1460-2431
    Source: JSTOR Ecology & Botany II
    Source: Alma/SFX Local Collection
    Source: Oxford Journals 2016 Current and Archive A-Z Collection
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  • 2
    Language: English
    In: Journal of phycology, 2014-08, Vol.50 (4), p.652-664
    Description: Members of various algal lineages are known to be strong producers of atmospherically relevant halogen emissions, that is a consequence of their capability to store and metabolize halogens. This study uses a noninvasive, synchrotron‐based technique, X‐ray absorption spectroscopy, for addressing in vivo bromine speciation in the brown algae Ectocarpus siliculosus, Ascophyllum nodosum, and Fucus serratus, the red algae Gracilaria dura, G. gracilis, Chondrus crispus, Osmundea pinnatifida, Asparagopsis armata, Polysiphonia elongata, and Corallina officinalis, the diatom Thalassiosira rotula, the dinoflagellate Lingulodinium polyedrum and a natural phytoplankton sample. The results highlight a diversity of fundamentally different bromine storage modes: while most of the stramenopile representatives and the dinoflagellate store mostly bromide, there is evidence for Br incorporated in nonaromatic hydrocarbons in Thalassiosira. Red algae operate various organic bromine stores – including a possible precursor (by the haloform reaction) for bromoform in Asparagopsis and aromatically bound Br in Polysiphonia and Corallina. Large fractions of the bromine in the red algae G. dura and C. crispus and the brown alga F. serratus are present as Br− defects in solid KCl, similar to what was reported earlier for Laminaria parts. These results are discussed according to different defensive strategies that are used within algal taxa to cope with biotic or abiotic stresses.
    Subject(s): microalgae ; extended X-ray absorption fine structure ; red algae ; X-ray absorption spectroscopy ; brown algae ; extended X‐ray absorption fine structure ; X‐ray absorption spectroscopy ; Marine sciences
    ISSN: 0022-3646
    E-ISSN: 1529-8817
    Source: Academic Search Ultimate
    Source: Alma/SFX Local Collection
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  • 3
    Language: English
    In: Critical care medicine, 2013-12, Vol.41, p.A249
    ISSN: 0090-3493
    E-ISSN: 1530-0293
    Source: Hellenic Academic Libraries Link
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  • 4
    Article
    Article
    2016
    ISSN: 0031-4005 
    Language: English
    In: Pediatrics (Evanston), 2016-10, Vol.138 (4), p.e20162398-e20162398
    Description: Concerns about bone health and potential fragility in children and adolescents have led to a high interest in bone densitometry. Pediatric patients with genetic and acquired chronic diseases, immobility, and inadequate nutrition may fail to achieve expected gains in bone size, mass, and strength, leaving them vulnerable to fracture. In older adults, bone densitometry has been shown to predict fracture risk and reflect response to therapy. The role of densitometry in the management of children at risk of bone fragility is less clear. This clinical report summarizes current knowledge about bone densitometry in the pediatric population, including indications for its use, interpretation of results, and risks and costs. The report emphasizes updated consensus statements generated at the 2013 Pediatric Position Development Conference of the International Society of Clinical Densitometry by an international panel of bone experts. Some of these recommendations are evidence-based, whereas others reflect expert opinion, because data are sparse on many topics. The statements from this and other expert panels provide general guidance to the pediatrician, but decisions about ordering and interpreting bone densitometry still require clinical judgment. The interpretation of bone densitometry results in children differs from that in older adults. The terms "osteopenia" and "osteoporosis" based on bone densitometry findings alone should not be used in younger patients; instead, bone mineral content or density that falls 〉2 SDs below expected is labeled "low for age." Pediatric osteoporosis is defined by the Pediatric Position Development Conference by using 1 of the following criteria: ≥1 vertebral fractures occurring in the absence of local disease or high-energy trauma (without or with densitometry measurements) or low bone density for age and a significant fracture history (defined as ≥2 long bone fractures before 10 years of age or ≥3 long bone fractures before 19 years of age). Ongoing research will help define the indications and best methods for assessing bone strength in children and the clinical factors that contribute to fracture risk. The Pediatric Endocrine Society affirms the educational value of this publication.
    Subject(s): Bone Density ; Fractures, Bone - etiology ; Calcium, Dietary - administration & dosage ; Humans ; Adolescent ; Bone Diseases, Metabolic - diagnosis ; Risk ; Vitamin D - analogs & derivatives ; Absorptiometry, Photon ; Child ; Practice Guidelines as Topic ; Vitamin D - blood ; Analysis ; Bone densitometry ; Youth ; Teenagers ; Research ; Children ; Health aspects ; Child health ; Abridged Index Medicus
    ISSN: 0031-4005
    E-ISSN: 1098-4275
    Source: Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
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  • 5
    Language: English
    In: Critical care medicine, 2012-12, Vol.40, p.1-328
    ISSN: 0090-3493
    E-ISSN: 1530-0293
    Source: Hellenic Academic Libraries Link
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  • 6
    Language: English
    In: The Journal of thoracic and cardiovascular surgery, 2008, Vol.136 (3), p.788-789.e3
    Description: Byline: Marie-Sophie Kupper (a), Noella Bethuyne (b), Jean Rubay (b), Francois Verhelst (b), Catherine Barrea (a), Stephane Moniotte (a) Author Affiliation: (a) Department of Pediatric Cardiology, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Brussels, Belgium (b) Department of Cardiac Surgery, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Brussels, Belgium Article History: Received 8 October 2007; Accepted 1 February 2008
    Subject(s): Cardiothoracic Surgery ; Cardiology. Vascular system ; Biological and medical sciences ; Medical sciences ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Pneumology ; Echocardiography ; Coronary Vessel Anomalies - surgery ; Humans ; Adolescent ; Child, Preschool ; Magnetic Resonance Angiography ; Coronary Vessel Anomalies - pathology ; Female ; Sinus of Valsalva - abnormalities ; Abridged Index Medicus
    ISSN: 0022-5223
    E-ISSN: 1097-685X
    Source: Alma/SFX Local Collection
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  • 7
    Language: English
    In: Pediatrics (Evanston), 2014-02, Vol.133 (2), p.e477-e489
    Description: Fractures are common injuries caused by child abuse. Although the consequences of failing to diagnose an abusive injury in a child can be grave, incorrectly diagnosing child abuse in a child whose fractures have another etiology can be distressing for a family. The aim of this report is to review recent advances in the understanding of fracture specificity, the mechanism of fractures, and other medical diseases that predispose to fractures in infants and children. This clinical report will aid physicians in developing an evidence-based differential diagnosis and performing the appropriate evaluation when assessing a child with fractures.
    Subject(s): Diagnosis, Differential ; Fractures, Bone - etiology ; Fractures, Bone - diagnosis ; Child ; Humans ; Child Abuse ; Child abuse ; Fractures ; Influence ; Infants ; Children ; Diagnosis ; Health aspects ; Risk factors ; Fractures (Injuries) ; Abridged Index Medicus
    ISSN: 0031-4005
    E-ISSN: 1098-4275
    Source: Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
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  • 8
    Language: English
    In: Women's health issues, 2008-03, Vol.18 (2), p.130-140
    Description: This study examines links between women's experiences of violence during adulthood (including physical and sexual violence) and women's physical health, mental health, and functional status. Data were analyzed from a representative sample of 9,830 North Carolina women surveyed by the North Carolina Behavioral Risk Factor Surveillance System (BRFSS). One-quarter of the women experienced violence as adults, with current or ex-partners being the most common perpetrators. Logistic regression analyses that controlled for the sociodemographic characteristics of the women found that women who experienced violence were significantly more likely than other women to have poor physical health, poor mental health, and functional limitations. Moreover, these negative health outcomes were most prevalent among the women who experienced a combination of both physical and sexual violence. These findings underscore the need for trauma-informed women's health services and policies.
    Subject(s): Prevalence ; Women's Health ; Crime Victims - statistics & numerical data ; Crime Victims - psychology ; Humans ; Middle Aged ; Spouse Abuse - statistics & numerical data ; Battered Women - psychology ; Logistic Models ; Spouses ; Mental Health ; Battered Women - statistics & numerical data ; Socioeconomic Factors ; Spouse Abuse - psychology ; Adult ; Female ; Surveys and Questionnaires ; Aged ; Health Status ; Interpersonal Relations ; North Carolina - epidemiology
    ISSN: 1049-3867
    E-ISSN: 1878-4321
    Source: Backfile Package - All of Back Files EBS [ALLOFBCKF]
    Source: Sociological Abstracts
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  • 9
    Language: English
    In: Journal of the American Chemical Society, 2005-11-09, Vol.127 (44), p.15340-15341
    Description: On the basis of EXAFS and MS/MS experimental results and a reinterpretation of the electron density map obtained by X-ray crystallography, we describe a new post-translational modification, that is, a 3,5-dibromotyrosine residue that is incorporated in the polypeptide chain of a vanadium haloperoxidase.
    Subject(s): Fundamental and applied biological sciences. Psychology ; Biological and medical sciences ; Structure in molecular biology ; Molecular biophysics ; Crystalline structure ; Tyrosine - metabolism ; Bromine - metabolism ; Peroxidases - chemistry ; Phaeophyta - enzymology ; X-Rays ; Peroxidases - metabolism ; Protein Processing, Post-Translational ; Spectrum Analysis ; Tyrosine ; Bromine ; Chemical properties ; Structure ; Vanadium
    ISSN: 0002-7863
    E-ISSN: 1520-5126
    Source: Hellenic Academic Libraries Link
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  • 10
    Language: English
    In: Women's health issues, 2008, Vol.18 (2), p.130-140
    Description: Objective This study examines links between women’s experiences of violence during adulthood (including physical and sexual violence) and women’s physical health, mental health, and functional status. Methods Data were analyzed from a representative sample of 9,830 North Carolina women surveyed by the North Carolina Behavioral Risk Factor Surveillance System (BRFSS). Results One-quarter of the women experienced violence as adults, with current or ex-partners being the most common perpetrators. Logistic regression analyses that controlled for the sociodemographic characteristics of the women found that women who experienced violence were significantly more likely than other women to have poor physical health, poor mental health, and functional limitations. Moreover, these negative health outcomes were most prevalent among the women who experienced a combination of both physical and sexual violence. Conclusions These findings underscore the need for trauma-informed women’s health services and policies.
    Subject(s): Obstetrics and Gynecology ; Women ; Health aspects
    ISSN: 1049-3867
    E-ISSN: 1878-4321
    Source: Backfile Package - All of Back Files EBS [ALLOFBCKF]
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