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  • 1
    Language: English
    In: TechTrends, 2011-02-06, Vol.55 (2), p.31-38
    Description: Understanding the covert events surrounding the undergraduate students’ experience is essential to educators’ and counselors’ involvement in their success. Research into bullying behaviors has documented victims’ feelings of anger, sadness and poor concentration. Affordable technologies have propagated this concern into cyberspace. This exploratory study evaluated the instances of cyberbullying experienced by undergraduate students. Additionally, the forms of technology utilized in cyberbullying were queried. A 27-item survey was distributed to 120 undergraduate students in social science, technology and education departments. The majority of all respondents (54%) and 100% of male respondents indicated they knew someone who had been cyberbullied. The perpetrators primarily used cell phones, Facebook and instant messaging. The study results provide legitimate concerns regarding the undergraduate students’ exposure to cyberbullying and numerous areas for future research.
    Subject(s): Article ; Bullying ; College students ; Cyberbullying ; Education ; Educational Technology ; Instant messaging ; Internet ; Learning and Instruction ; Studies ; Universities and colleges ; University students
    ISSN: 8756-3894
    E-ISSN: 1559-7075
    Source: Academic Search Ultimate
    Source: Alma/SFX Local Collection
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  • 2
    Language: English
    In: Near and Middle Eastern Journal of Research in Education, 2015-02-01, Vol.2015 (1)
    Description: While numerous studies have been conducted on the impact of nicknames on students, these studies have focused on the effects of nicknames students have received in their lives. This study adopted a very unique and different design and asked female Kuwaiti university students to self-select a nickname of their own choice to be used in the classroom instead of their proper name. The students who volunteered to self-select nicknames and the students who did not were administered a structured questionnaire that was designed to gather data regarding the perceptions of the effects the self-selected nicknames had upon classroom performance. The analysis of the surveys revealed that the female students who selected nicknames reported that it improved their classroom performance. In addition, the females who did not select a nickname reported that it appeared to improve the classroom performance of those who choose a nickname.
    ISSN: 1703-1958
    E-ISSN: 1703-1958
    Source: Freely Accessible Journals
    Source: Arab World Research Source
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  • 3
    Language: English
    In: Western journal of communication, 1996-03-01, Vol.60 (1), p.76-91
    Description: Conversation analysis has enjoyed recent acceptance in mainstream communication research. Despite successes, it remains criticized by quantitative researchers for a variety of reasons. One such reason is that, to date, conversation analysts have not felt obligated to demonstrate "inter-transcriber" reliability for the use of transcription notation. This paper argues for determining ways to address this criticism. Toward that end, 22 participants were asked to transcribe a randomly selected segment of naturally occurring conversation. The transcripts were compared and percentages of agreement were computed for overall agreement as well as agreement regarding verbal content, pauses, overlaps, and intonation. Additionally, education level was considered as a predictor of transcription agreement. Results indicate that multiple transcribers are capable of producing similar transcripts within the acceptable tolerances of a priori coding schemes. With the exception of pauses, all transcription notations were agreed upon at a rate of 75% or better. The data also suggest that there is very little difference in transcript accuracy rates between undergraduates and graduate students. Thus, education level on this dimension does not appear to have an affect.
    Subject(s): Analysis ; Communication ; Conversation analysis ; Intonation ; Pauses
    ISSN: 1057-0314
    E-ISSN: 1745-1027
    Source: Communication & Mass Media Complete
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  • 4
    Book chapter
    Book chapter
    2015
    ISBN: 9780127999319  ISBN: 9780127999364  ISBN: 0127999361  ISBN: 0127999310 
    Language: English
    In: Forest Plans of North America, 2015, p.139-148
    Description: The sustainable management of Maryland’s Chesapeake Forest Lands began in 2000 through collaboration between the Maryland Department of Natural Resources Forest Service and The Conservation Fund and continues today with a mix of public land managers and private contractors. The Conservation Fund, acting for the Richard King Mellon Foundation, acquired 29,000 acres (ac) (11,736 hectares (ha)) of former industrial forests on Maryland’s eastern shore, while the state of Maryland purchased an additional 29,000ac from the same ownership. The Conservation Fund then gifted its land to Maryland, but with a unique twist; it came with a sustainable forest management plan with a commitment to meet environmental goals while supporting the local economy. The result is a state-owned forest with daily silvicultural operations being carried out by a private forestry firm overseen by a state land manager, dual-certified through the Sustainable Forestry Initiative and Forest Stewardship Council. This uncommon arrangement in state land management has created new challenges and opportunities, which offer lessons learned that transfer well beyond these forests.
    Subject(s): Delmarva Bays ; Endangered species habitat management ; Public-private partnership ; Sustainable forest management
    ISBN: 9780127999319
    ISBN: 9780127999364
    ISBN: 0127999361
    ISBN: 0127999310
    Source: Ebook Central - Academic Complete
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  • 5
    Language: English
    In: Communication research reports, 1998-09-01, Vol.15 (4), p.406-412
    Description: Verbal aggressiveness is the tendency to attack the self-concept of another person with the intent to inflict psychological pain (Infante & Wigley, 1986). This study focused on how low and high verbally aggressives differ in the television sitcoms they watch and how enjoyable they find those shows. Participants (N = 555) first completed the Verbal Aggressiveness Scale. Then they were asked how often they watch particular television sitcoms and if they watched a given sitcom, how entertaining they found that show to be. The sitcoms included in this study were those that were televised in April 1996. Of the 33 shows included in the analyses, low verbal aggressives differed from high verbal aggressives on 8 shows for frequency of watching and on 11 shows for entertainment value.
    ISSN: 0882-4096
    E-ISSN: 1746-4099
    Source: Communication & Mass Media Complete
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  • 6
    Dissertation
    Dissertation
    1998
    ISBN: 9780591761641  ISBN: 0591761645 
    Language: English
    Description: The purpose of this study was to construct a student perception of a teacher's health scale. The rationale for the study was the severe lack of research on the effects of a teacher's health in the classroom environment. In addition, the tremendous dropout rate in the teaching profession due to burnout, stress and other health related factors was a key ingredient. Scale construction was deemed an important beginning component in investigation of an area with little prior investigation. The original scale was designed using student focus group participation. A sample of 54 undergraduate subjects were interviewed and audio-taped. Analysis of the interviews resulted in an original 75 item scale being constructed from the focus group procedure. Three hundred subjects completed the 75 item scale survey and these scales were used for factor analysis and correlation analysis procedures. The final scale construction resulted in a 20 item survey. The scree plot indicates a strong unidimensional scale. Factor loadings for 17 of the 20 items is above.70, with 2 items above.80. Cronbach reliability for the 20 item scale was.96. The test-retest reliability score was.86. Areas for future research were suggested.
    Subject(s): Health education ; Higher education
    ISBN: 9780591761641
    ISBN: 0591761645
    Source: ProQuest Dissertations & Theses Global
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  • 7
    Language: English
    In: Blood, 2010-12-16, Vol.116 (25), p.5738-5747
    Description: Myeloid-derived suppressor cells (MDSCs) are a well-defined population of cells that accumulate in the tissue of tumor-bearing animals and are known to inhibit immune responses. Within 4 days, bone marrow cells cultured in granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor resulted in the generation of CD11b+Ly6GloLy6C+ MDSCs, the majority of which are interleukin-4Rα (IL-4Rα+) and F4/80+. Such MDSCs potently inhibited in vitro allogeneic T-cell responses. Suppression was dependent on L-arginine depletion by arginase-1 activity. Exogenous IL-13 produced an MDSC subset (MDSC-IL-13) that was more potently suppressive and resulted in arginase-1 up-regulation. Suppression was reversed with an arginase inhibitor or on the addition of excess L-arginine to the culture. Although both MDSCs and MDSC-IL-13 inhibited graft-versus-host disease (GVHD) lethality, MDSC-IL-13 were more effective. MDSC-IL-13 migrated to sites of allopriming. GVHD inhibition was associated with limited donor T-cell proliferation, activation, and proinflammatory cytokine production. GVHD inhibition was reduced when arginase-1-deficient MDSC-IL-13 were used. MDSC-IL-13 did not reduce the graft-versus-leukemia effect of donor T cells. In vivo administration of a pegylated form of human arginase-1 (PEG-arg1) resulted in L-arginine depletion and significant GVHD reduction. MDSC-IL-13 and pegylated form of human arginase-1 represent novel strategies to prevent GVHD that can be clinically translated.
    Subject(s): Abridged Index Medicus ; Animals ; Arginase - metabolism ; Biological and medical sciences ; Bone Marrow Cells - drug effects ; Bone Marrow Cells - metabolism ; Bone Marrow Transplantation ; Cells, Cultured ; Graft vs Host Disease - enzymology ; Graft vs Host Disease - prevention & control ; Granulocyte Colony-Stimulating Factor - metabolism ; Granulocyte-Macrophage Colony-Stimulating Factor - metabolism ; Hematologic and hematopoietic diseases ; Humans ; Immunoblotting ; Interleukin-13 - pharmacology ; Lymphocyte Activation ; Medical sciences ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Protein-Serine-Threonine Kinases - physiology ; T-Lymphocytes - cytology ; T-Lymphocytes - drug effects ; T-Lymphocytes - metabolism ; Transplantation ; Up-Regulation
    ISSN: 0006-4971
    E-ISSN: 1528-0020
    Source: Alma/SFX Local Collection
    Source: American Society of Hematology
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  • 8
    Language: English
    In: Nature communications, 2017-10-31, Vol.8 (1), p.1206-10
    Description: Erythromycin, avermectin and rapamycin are clinically useful polyketide natural products produced on modular polyketide synthase multienzymes by an assembly-line process in which each module of enzymes in turn specifies attachment of a particular chemical unit. Although polyketide synthase encoding genes have been successfully engineered to produce novel analogues, the process can be relatively slow, inefficient, and frequently low-yielding. We now describe a method for rapidly recombining polyketide synthase gene clusters to replace, add or remove modules that, with high frequency, generates diverse and highly productive assembly lines. The method is exemplified in the rapamycin biosynthetic gene cluster where, in a single experiment, multiple strains were isolated producing new members of a rapamycin-related family of polyketides. The process mimics, but significantly accelerates, a plausible mechanism of natural evolution for modular polyketide synthases. Detailed sequence analysis of the recombinant genes provides unique insight into the design principles for constructing useful synthetic assembly-line multienzymes.
    Subject(s): Assembly lines ; Avermectin ; Bioengineering ; Biological evolution ; Biosynthesis ; Biosynthetic Pathways - genetics ; Clusters ; Erythromycin ; Evolution, Molecular ; Evolutionary genetics ; Gene clusters ; Genes ; Genetic Variation ; Multigene Family ; Natural products ; Polyketide synthase ; Polyketide Synthases - genetics ; Polyketides ; Rapamycin ; Reengineering ; Sirolimus - chemistry ; Sirolimus - metabolism
    ISSN: 2041-1723
    E-ISSN: 2041-1723
    Source: Nature Open Access
    Source: PubMed Central
    Source: DOAJ Directory of Open Access Journals - Not for CDI Discovery
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  • 9
    Language: English
    In: BMC neurology, 2016-05-04, Vol.16 (1), p.61-61
    Description: Patients with a history of mild TBI (post-mTBI-patients) have an unexplained increase in long-term mortality which might be related to central autonomic dysregulation (CAD). We investigated whether standardized baroreflex-loading, induced by a Valsalva maneuver (VM), unveils CAD in otherwise healthy post-mTBI-patients. In 29 healthy persons (31.3 ± 12.2 years; 9 women) and 25 post-mTBI-patients (35.0 ± 13.2 years, 7 women, 4-98 months post-injury), we monitored respiration (RESP), RR-intervals (RRI) and systolic blood pressure (BP) at rest and during three VMs. At rest, we calculated parameters of total autonomic modulation [RRI-coefficient-of-variation (CV), RRI-standard-deviation (RRI-SD), RRI-total-powers], of sympathetic [RRI-low-frequency-powers (LF), BP-LF-powers] and parasympathetic modulation [square-root-of-mean-squared-differences-of-successive-RRIs (RMSSD), RRI-high-frequency-powers (HF)], the index of sympatho-vagal balance (RRI LF/HF-ratios), and baroreflex sensitivity (BRS). We calculated Valsalva-ratios (VR) and times from lowest to highest RRIs after strain (VR-time) as indices of parasympathetic activation, intervals from highest systolic BP-values after strain-release to the time when systolic BP had fallen by 90 % of the differences between peak-phase-IV-BP and baseline-BP (90 %-BP-normalization-times), and velocities of BP-normalization (90 %-BP-normalization-velocities) as indices of sympathetic withdrawal. We compared patient- and control-parameters before and during VM (Mann-Whitney-U-tests or t-tests; significance: P 〈 0.05). At rest, RRI-CVs, RRI-SDs, RRI-total-powers, RRI-LF-powers, BP-LF-powers, RRI-RMSSDs, RRI-HF-powers, and BRS were lower in patients than controls. During VMs, 90 %-BP-normalization-times were longer, and 90 %-BP-normalization-velocities were lower in patients than controls (P 〈 0.05). Reduced autonomic modulation at rest and delayed BP-decrease after VM-induced baroreflex-loading indicate subtle CAD with altered baroreflex adjustment to challenge. More severe autonomic challenge might trigger more prominent cardiovascular dysregulation and thus contribute to increased mortality risk in post-mTBI-patients.
    Subject(s): Adult ; Amnesia ; Amygdala ; Apnea ; Arteriosclerosis ; Autonomic nervous system ; Autonomic Nervous System Diseases - physiopathology ; Baroreceptors ; Baroreflex ; Baroreflex dysfunction ; Blood Pressure ; Blood pressure overshoot ; Brain ; Brain Concussion - physiopathology ; Cardiovascular system ; Care and treatment ; Case-Control Studies ; Central autonomic network ; Complications and side effects ; Consciousness ; Disability ; Emotions ; Fatalities ; Female ; Heart diseases ; Heart rate ; Heart Rate - physiology ; Humans ; Hyperactivity ; Injuries ; Kidney diseases ; Kidney transplantation ; Male ; Metabolic disorders ; Mild traumatic brain injury ; Mortality ; pH effects ; Reflexes ; Research ; Respiration ; Risk factors ; Shores ; Skull ; Surgery ; Sympathetic dysregulation ; Syncope ; Temperature effects ; Traumatic brain injury ; Valsalva Maneuver
    ISSN: 1471-2377
    E-ISSN: 1471-2377
    Source: BioMedCentral Open Access
    Source: Academic Search Ultimate
    Source: PubMed Central
    Source: DOAJ Directory of Open Access Journals - Not for CDI Discovery
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  • 10
    Language: English
    In: Journal of neurology, 2017-08-02, Vol.264 (9), p.1956-1967
    Description: After traumatic brain injury (TBI), central autonomic dysfunction might contribute to long-term increased mortality rates. Central autonomic dysfunction might depend on initial trauma severity. This study was performed to evaluate differences in autonomic modulation at rest and upon standing between patients with a history of mild TBI (post-mild-TBI patients), moderate or severe TBI (post-moderate–severe-TBI patients), and healthy controls. In 20 post-mild-TBI patients (6–78 months after TBI), age-matched 20 post-moderate–severe-TBI patients (6–94 months after TBI) and 20 controls, we monitored respiration, RR intervals (RRI) and systolic blood pressure (BPsys) at supine rest and upon standing. We determined mainly sympathetic low (LF) and parasympathetic high (HF) frequency powers of RRI fluctuations, sympathetically mediated LF-BPsys powers, LF/HF-RRI ratios, normalized (nu) LF-RRI and HF-RRI powers, and compared data between groups, at rest and upon standing (ANOVA with post hoc testing). We correlated autonomic parameters with initial Glasgow Coma Scale (GCS) scores (Spearman test; significance: p  〈 0.05). Supine BPsys and LFnu-RRI powers were higher while HFnu-RRI powers were lower in post-moderate–severe-TBI patients than post-mild-TBI patients and controls. LFnu-RRI powers were higher and HFnu-RRI powers were lower in post-mild-TBI patients than controls. Upon standing, only post-mild-TBI patients and controls increased LF-BPsys powers and BPsys and decreased HF-RRI powers. GCS scores correlated positively with LFnu-RRI powers, LF/HF-RRI ratios, and inversely with HFnu-RRI powers, at standing position. More than 6 months after TBI, there is autonomic dysfunction at rest and upon standing which is more pronounced after moderate–severe than mild TBI and in part correlates with initial trauma severity.
    Subject(s): Adolescent ; Adult ; Analysis of Variance ; Autonomic dysfunction ; Autonomic Nervous System Diseases - complications ; Autonomic Nervous System Diseases - diagnosis ; Blood pressure ; Blood Pressure - physiology ; Brain ; Brain Injuries, Traumatic - complications ; Brain Injuries, Traumatic - diagnosis ; Cardiovascular diseases ; Cardiovascular Diseases - complications ; Cardiovascular Diseases - diagnosis ; Case-Control Studies ; Coma ; Complications and side effects ; Differences in severity ; Female ; Glasgow Coma Scale ; Heart Rate - physiology ; Humans ; Injuries ; Longitudinal Studies ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Neurology ; Neuroradiology ; Neurosciences ; Original Communication ; Orthostatic challenge ; Parasympathetic nervous system ; Posture ; Prognosis ; Risk factors ; Statistics, Nonparametric ; Trauma ; Traumatic brain injury ; Young Adult
    ISSN: 0340-5354
    E-ISSN: 1432-1459
    Source: Alma/SFX Local Collection
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