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  • 1
    Article
    Article
    2016
    ISSN: 2090-8016  ISSN: 2090-0597 
    Language: English
    In: Cardiology research and practice, 2016-02-18, Vol.2016, p.2579832-12
    Description: Heart failure is a chronic disease with high morbidity and mortality, which represents a growing challenge in medicine. A major risk factor for heart failure with reduced ejection fraction is a history of myocardial infarction. The expansion of a large infarct scar and subsequent regional ventricular dilatation can cause postinfarct remodelling, leading to significant enlargement of the left ventricular chamber. It has a negative prognostic value, because it precedes the clinical manifestations of heart failure. The characteristics of the infarcted myocardium predicting postinfarct remodelling can be studied with cardiac magnetic resonance and experimental imaging modalities such as diffusion tensor imaging can identify the changes in the architecture of myocardial fibers. This review discusses all the aspects related to postinfarct left ventricular remodelling: definition, pathogenesis, diagnosis, consequences, and available therapies, together with experimental interventions that show promising results against postinfarct remodelling and heart failure.
    Subject(s): Heart failure ; Heart ; Chronic diseases ; Heart enlargement ; Risk factors ; Heart attack ; Hospitals ; Heart attacks ; Cardiomyopathy ; Womens health ; Pathogenesis ; Mortality ; Cardiovascular disease ; Ejection fraction ; Review
    ISSN: 2090-8016
    ISSN: 2090-0597
    E-ISSN: 2090-0597
    Source: Academic Search Ultimate
    Source: PubMed Central
    Source: Directory of Open Access Journals
    Source: ProQuest Central
    Source: © ProQuest LLC All rights reserved〈img src="https://exlibris-pub.s3.amazonaws.com/PQ_Logo.jpg" style="vertical-align:middle;margin-left:7px"〉
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  • 2
    Language: English
    In: The Journal of physiology, 2019-05-15, Vol.597 (10), p.2595-2598
    Subject(s): Heart rate ; Provocative tests ; Autonomopathy ; Neuropathy ; Autonomic nervous system ; Heart rate variability ; Heart beat ; Index Medicus ; CrossTalk
    ISSN: 0022-3751
    E-ISSN: 1469-7793
    Source: Hellenic Academic Libraries Link
    Source: PubMed Central
    Source: © ProQuest LLC All rights reserved〈img src="https://exlibris-pub.s3.amazonaws.com/PQ_Logo.jpg" style="vertical-align:middle;margin-left:7px"〉
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  • 3
    Language: English
    In: Journal of the American College of Cardiology, 2013, Vol.61 (8), p.870-871
    Subject(s): Cardiovascular ; Internal Medicine ; ST-segment elevation ; J waves ; sudden cardiac death ; Cardiovascular Diseases ; Heart Conduction System - physiopathology ; Humans ; Female ; Male ; Electrophysiological Phenomena ; Electrocardiography - methods ; Index Medicus ; Abridged Index Medicus
    ISSN: 0735-1097
    E-ISSN: 1558-3597
    Source: Alma/SFX Local Collection
    Source: © ProQuest LLC All rights reserved〈img src="https://exlibris-pub.s3.amazonaws.com/PQ_Logo.jpg" style="vertical-align:middle;margin-left:7px"〉
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  • 4
    Language: English
    In: Remote sensing (Basel, Switzerland), 2019-05-07, Vol.11 (9), p.1075
    Description: Soil morphology plays a fundamental role in the vertical and lateral movements of solutes and water transport, providing knowledge regarding spatial distribution of its textural properties and subsurface dynamics. In this framework, the measured values of electrical conductivity are able to reveal the heterogeneity of soil that is present in a particular agricultural field and they are affected by more than one important physical characteristic: soil texture, organic matter, moisture content, and the depth of the clay pan. In the microwave region, these dynamics are known to exhibit a frequency dependent behaviour. This study explores the application of a Step Frequency Continuous Wave Ground Penetrating Radar (SFCW GPR) to shed light on the practical impact that these dependencies have on the imaging results, not only regarding the electrical characterisation of the subsurface morphology, but also in its correct interpretation. This information is of notable importance for determining water-use efficiency and planning precision-agriculture programs. The results clearly show visible and significant fluctuations of the amplitude levels, depending on the considered central frequency, demonstrating that the frequency dependence of electromagnetic properties of heterogeneous soil are significant and cannot be ignored if the aim is to properly define the subsurface attributes. The measurements also suggest that correlating the delineated variations might help in the identification of extended features and the classification of areas that possess similar properties in order to increase the confidence in monitoring soil resources.
    Subject(s): Precision agriculture ; Soil electromagnetic properties ; soil characterisation ; GPR frequency dependency effects ; Step-Frequency Ground Penetrating Radar
    ISSN: 2072-4292
    E-ISSN: 2072-4292
    Source: Academic Search Ultimate
    Source: Directory of Open Access Journals
    Source: ProQuest Central
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  • 5
    Language: English
    In: IEEE geoscience and remote sensing letters, 2019-03, Vol.16 (3), p.362-366
    Description: The effectiveness of the ground penetrating radar (GPR) imaging process and its capability of correctly reconstructing buried objects is strictly bounded to a correct acquisition strategy, both in terms of data density and regularity. In some GPR applications, such as landmine detection, these requirements may not be fulfiled due to logistical limitations and environmental obstacles. In the light of autonomous platform, possibly driven by a positioning device, the knowledge of the maximum affordable grid irregularity is essential. This experimental work, employing a data set acquired at a landmine test site, provides a demonstration that the same information content could be maintained even with a sparser data grid, compared to the commonly adopted requirements, mitigating the pressing demand for a precise samples positioning.
    Subject(s): Degradation ; Ground penetrating radar ; Landmine detection ; Correlation ; Ground penetrating radar (GPR) ; landmine imaging ; trace positioning ; Soil ; Radar imaging ; radar image reconstruction ; Image reconstruction
    ISSN: 1545-598X
    E-ISSN: 1558-0571
    Source: IEEE Electronic Library (IEL)
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  • 6
    Language: English
    In: Scientific reports, 2020-07-15, Vol.10 (1), p.11661-11661
    Description: Mild cognitive impairment (MCI) is a heterogeneous syndrome with two main clinical subtypes, amnestic (aMCI) and non-amnestic (naMCI). The analysis of heart rate variability (HRV) is a tool to assess autonomic function. Cognitive and autonomic processes are linked via the central autonomic network. Autonomic dysfunction entails several adverse outcomes. However, very few studies have investigated autonomic function in MCI and none have considered MCI subtypes or the relationship of HRV indices with different cognitive domains and structural brain damage. We assessed autonomic function during an active orthostatic challenge in 253 oupatients aged ≥ 65, [n = 82 aMCI, n = 93 naMCI, n = 78 cognitively normal (CN), neuropsychologically tested] with power spectral analysis of HRV. We used visual rating scales to grade cerebrovascular burden and hippocampal/insular atrophy (HA/IA) on neuroimaging. Only aMCI showed a blunted response to orthostasis. Postural changes in normalised low frequency (LF) power and in the LF to high frequency ratio correlated with a memory test (positively) and HA/IA (negatively) in aMCI, and with attention/executive function tests (negatively) and cerebrovascular burden (positively) in naMCI. These results substantiate the view that the ANS is differentially impaired in aMCI and naMCI, consistently with the neuroanatomic substrate of Alzheimer's and small-vessel subcortical ischaemic disease.
    Subject(s): Neuroimaging ; Humans ; Male ; Autonomic Nervous System - physiopathology ; Hippocampus - diagnostic imaging ; Cerebral Cortex - physiopathology ; Attention - physiology ; Aged, 80 and over ; Heart Rate - physiology ; Female ; Cognitive Dysfunction - diagnostic imaging ; Heart - physiopathology ; Severity of Illness Index ; Cross-Sectional Studies ; Amnesia - diagnostic imaging ; Autonomic Nervous System - diagnostic imaging ; Cognitive Dysfunction - physiopathology ; Executive Function - physiology ; Cerebral Cortex - diagnostic imaging ; Heart - diagnostic imaging ; Neuropsychological Tests ; Amnesia - physiopathology ; Dizziness - physiopathology ; Aged ; Dizziness - diagnostic imaging ; Postural Balance - physiology ; Hippocampus - physiopathology ; Memory - physiology ; Atrophy ; Heart rate ; Executive function ; Brain architecture ; Neurodegenerative diseases ; Autonomic nervous system ; Cognitive ability ; Anatomy ; Alzheimer's disease ; Hippocampus ; Brain injury ; Index Medicus
    ISSN: 2045-2322
    E-ISSN: 2045-2322
    Source: Nature Open Access
    Source: Academic Search Ultimate
    Source: PubMed Central
    Source: Directory of Open Access Journals
    Source: © ProQuest LLC All rights reserved〈img src="https://exlibris-pub.s3.amazonaws.com/PQ_Logo.jpg" style="vertical-align:middle;margin-left:7px"〉
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  • 7
    Language: English
    In: Journal of the American College of Cardiology, 2008, Vol.52 (17), p.1353-1365
    Description: This consensus statement has been compiled on behalf of the International Society for Holter and Noninvasive Electrophysiology. It reviews the topic of heart rate turbulence (HRT) and concentrates on technologies for measurement, physiologic background and interpretation, and clinical use of HRT. It also lists suggestions for future research. The phenomenon of HRT refers to sinus rhythm cycle-length perturbations after isolated premature ventricular complexes. The physiologic pattern of HRT consists of brief heart rate acceleration (quantified by the so-called turbulence onset) followed by more gradual heart rate deceleration (quantified by the so-called turbulence slope) before the rate returns to a pre-ectopic level. Available physiologic investigations confirm that the initial heart rate acceleration is triggered by transient vagal inhibition in response to the missed baroreflex afferent input caused by hemodynamically inefficient ventricular contraction. A sympathetically mediated overshoot of arterial pressure is responsible for the subsequent heart rate deceleration through vagal recruitment. Hence, the HRT pattern is blunted in patients with reduced baroreflex. The HRT pattern is influenced by a number of factors, provocations, treatments, and pathologies reviewed in this consensus. As HRT measurement provides an indirect assessment of baroreflex, it is useful in those clinical situations that benefit from baroreflex evaluation. The HRT evaluation has thus been found appropriate in risk stratification after acute myocardial infarction, risk prediction, and monitoring of disease progression in heart failure, as well as in several other pathologies.
    Subject(s): Cardiology. Vascular system ; Biological and medical sciences ; Medical sciences ; Vagus Nerve - physiology ; Prognosis ; Ventricular Function - physiology ; Heart Conduction System - physiopathology ; Risk Assessment ; Humans ; Heart Rate - physiology ; Baroreflex - physiology ; Consensus Development Conferences as Topic ; Arrhythmias, Cardiac - physiopathology ; Index Medicus ; Abridged Index Medicus
    ISSN: 0735-1097
    E-ISSN: 1558-3597
    Source: Alma/SFX Local Collection
    Source: © ProQuest LLC All rights reserved〈img src="https://exlibris-pub.s3.amazonaws.com/PQ_Logo.jpg" style="vertical-align:middle;margin-left:7px"〉
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  • 8
    Language: English
    In: Journal of nuclear cardiology, 2019-06, Vol.26 (3), p.833-840
    Description: The aim of the present study is to evaluate the additional value of systolic wall thickening to myocardial perfusion in diagnosing myocardial stunning in patients with angiography proven coronary artery disease. We selected 91 ischemic patients (82 males; mean age 59.7 ± 10.3) with CAD documented by angiography. Ischemia was defined as a summed difference score ≥5. All patients underwent a 2-day gated perfusion SPECT protocol. The patients received a dose of 740 MBq of Tc-tetrofosmin after stress and at rest. Treadmill maximal exercise tests were performed on all patients. The post-stress LVEF was significantly lower than rest LVEF (48.1% ± 10.3% vs 50.3% ± 10.7%; P = .0001). The wall thickening summed difference score was 4.44 ± 4.13 (P = .0001). At a multivariate regression analysis, only WT-SDS as independent variable was significantly correlated with myocardial ischemia (SDS). We also divided patients according to SDS in those with mild (SDS 〈 8) and severe (SDS ≥ 8) ischemia. WT-SDS, but not ∆LVEF, was significantly different between groups. WT-SDS, more than the depression in the global function (∆LVEF) of the left ventricle, correlates with the degree of ischemia and better identifies, when present, the stunning phenomenon.
    Subject(s): CT imaging ; SPECT imaging ; Coronary heart disease ; Analysis ; Cardiac patients ; Ischemia ; Cardiovascular disease ; Medical imaging ; Index Medicus ; DIAGNOSIS ; PATIENTS ; BIOMEDICAL RADIOGRAPHY ; CORONARIES ; RADIOLOGY AND NUCLEAR MEDICINE ; ISCHEMIA ; TECHNETIUM 99 ; EXERCISE ; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
    ISSN: 1071-3581
    ISSN: 1532-6551
    E-ISSN: 1532-6551
    Source: Alma/SFX Local Collection
    Source: © ProQuest LLC All rights reserved〈img src="https://exlibris-pub.s3.amazonaws.com/PQ_Logo.jpg" style="vertical-align:middle;margin-left:7px"〉
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  • 9
    Language: English
    In: Journal of the American College of Cardiology, 2016-11-15, Vol.68 (20), p.2166-2181
    Description: Cardiac magnetic resonance (CMR) is useful for the diagnosis of left ventricular noncompaction (LVNC). However, there are limited data regarding its prognostic value. The goal of this study was to evaluate the prognostic relevance of CMR findings in patients with LVNC. A total of 113 patients with an echocardiographic diagnosis of LVNC underwent CMR at 5 referral centers. CMR diagnostic criterion of LVNC (noncompacted/compacted ratio 〉2.3 in end-diastole) was confirmed in all patients. We performed left ventricular (LV) and right ventricular quantitative analysis and late gadolinium enhancement (LGE) assessments and analyzed the following LVNC diagnostic criteria: left ventricular noncompacted myocardial mass (LV-ncMM) 〉20% and 〉25%, total LV-ncMM index 〉15 g/m , noncompacted/compacted ratio ≥3:1 ≥1 of segments 1 to 3 and 7 to 16 or ≥2:1 in at least 1 of segments 4 to 6 of the American Heart Association model. Outcome was a composite of thromboembolic events, heart failure hospitalizations, ventricular arrhythmias, and cardiac death. At a mean follow-up of 48 ± 24 months, cardiac events (CEs) occurred in 36 patients (16 heart failure hospitalizations, 10 ventricular arrhythmias, 5 cardiac deaths, and 5 thromboembolic events). LV dilation, impaired LV ejection fraction, and LV-ncMM 〉20% was significantly more frequent in patients with CEs. LV fibrosis was detected by using LGE in 11 cases. CMR predictors of CEs were LV dilation and LGE. LGE was associated with improved prediction of CEs, compared with clinical data and CMR functional parameters in all 3 models. No CEs occurred in patients without dilated cardiomyopathy and/or LGE. In patients with LVNC evaluated by using CMR, the degree of LV trabeculation seems to have no prognostic impact over and above LV dilation, LV systolic dysfunction, and presence of LGE.
    Subject(s): Reproducibility of Results ; Echocardiography ; Prognosis ; Prospective Studies ; Follow-Up Studies ; Humans ; Middle Aged ; Male ; Heart Ventricles - diagnostic imaging ; Disease Progression ; Magnetic Resonance Imaging, Cine - methods ; Time Factors ; Adult ; Female ; Isolated Noncompaction of the Ventricular Myocardium - diagnosis ; Index Medicus ; Abridged Index Medicus
    E-ISSN: 1558-3597
    Source: Alma/SFX Local Collection
    Source: © ProQuest LLC All rights reserved〈img src="https://exlibris-pub.s3.amazonaws.com/PQ_Logo.jpg" style="vertical-align:middle;margin-left:7px"〉
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  • 10
    Language: English
    In: Sensors (Basel, Switzerland), 2020-09-23, Vol.20 (19), p.5450
    Description: Self-driving cars and autonomous vehicles are revolutionizing the automotive sector, shaping the future of mobility altogether. Although the integration of novel technologies such as Artificial Intelligence (AI) and Cloud/Edge computing provides golden opportunities to improve autonomous driving applications, there is the need to modernize accordingly the whole prototyping and deployment cycle of AI components. This paper proposes a novel framework for developing so-called AI Inference Engines for autonomous driving applications based on deep learning modules, where training tasks are deployed elastically over both Cloud and Edge resources, with the purpose of reducing the required network bandwidth, as well as mitigating privacy issues. Based on our proposed data driven V-Model, we introduce a simple yet elegant solution for the AI components development cycle, where prototyping takes place in the cloud according to the Software-in-the-Loop (SiL) paradigm, while deployment and evaluation on the target ECUs (Electronic Control Units) is performed as Hardware-in-the-Loop (HiL) testing. The effectiveness of the proposed framework is demonstrated using two real-world use-cases of AI inference engines for autonomous vehicles, that is environment perception and most probable path prediction.
    Subject(s): Index Medicus ; deep learning ; autonomous vehicles ; cloud computing ; edge computing ; artificial intelligence ; self-driving cars
    E-ISSN: 1424-8220
    Source: Academic Search Ultimate
    Source: PubMed Central
    Source: Directory of Open Access Journals
    Source: Alma/SFX Local Collection
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