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  • 1
    Book
    Book
    2011
    ISBN: 0838910815  ISBN: 9780838992944  ISBN: 0838992943  ISBN: 9780838910818 
    Language: English
    Description: In their definitive new Interlibrary Loan Practices Handbook, editors Weible and Janke clearly explain the complexities of getting materials for patrons from outside the library. This collection presents a complete view of the interlibrary loan (ILL) process, with contributions from all areas of the technical services community, providing * Guidance on how to do ILL efficiently and effectively, with advice on how to be a considerate borrower and lender * Details of preferred staffing and management techniques, showing how best practices can be implemented at any institution * Discussion of important issues that can fall between the cracks, such as hidden copyright issues, and the logistics of lending internationally Consortia and other library partnerships are now sharing ever larger fractions of their collections, and this book gives library staff the tools necessary for a smoothly functioning ILL system.
    Subject(s): United States ; Interlibrary loans ; Handbooks, manuals, etc
    ISBN: 0838910815
    ISBN: 9780838992944
    ISBN: 0838992943
    ISBN: 9780838910818
    Source: Ebook Central - Academic Complete
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Book chapter
    Book chapter
    2011
    ISBN: 0838910815  ISBN: 0838992943  ISBN: 9780838992944  ISBN: 9780838910818 
    Language: English
    In: Interlibrary Loan Practices Handbook, 2011-05-23
    Description: In their definitive new Interlibrary Loan Practices Handbook, editors Weible and Janke clearly explain the complexities of getting materials from outside the library for patrons. This collection presents a complete view of the interlibrary loan (ILL) process, with contributions from all areas of the technical services community, providing Guidance on how to do ILL efficiently and effectively, with advice on how to be a considerate borrower and lender Details of preferred staffing and management techniques, showing how best practices can be implemented at any institution Discussion of important issues that can fall between the cracks, such as hidden copyright issues, and the logistics of lending internationally Consortia and other library partnerships are now sharing ever larger fractions of their collections, and this book gives library staff the tools necessary for a smoothly functioning ILL system.
    Subject(s): Information science ; Interlibrary loans -- United States -- Handbooks, manuals, etc ; Library science ; Language arts ; Borrowing
    ISBN: 0838910815
    ISBN: 0838992943
    ISBN: 9780838992944
    ISBN: 9780838910818
    Source: Ebook Central - Academic Complete
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    Language: English
    In: Emerging infectious diseases, 2005-12, Vol.11 (12), p.1974-1976
    Subject(s): Letter ; greyhounds ; influenza virus ; hemorrhagic pneumonia ; Letters to the Editor ; canine ; H3N8 subtype ; letter
    ISSN: 1080-6040
    E-ISSN: 1080-6059
    Source: Academic Search Ultimate
    Source: PubMed Central
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  • 4
    Language: English
    In: Emerging infectious diseases, 2005-12, Vol.11 (12), p.1974-1976
    Subject(s): Dog Diseases - epidemiology ; Orthomyxoviridae Infections - veterinary ; Influenza A virus - isolation & purification ; Orthomyxoviridae Infections - epidemiology ; Animals ; Pneumonia, Viral - epidemiology ; Dogs ; Pneumonia, Viral - veterinary ; Disease Outbreaks - veterinary ; Iowa - epidemiology ; Orthomyxoviridae Infections - virology ; Pneumonia, Viral - virology ; Dog Diseases - virology ; Influenza viruses ; Development and progression ; Control ; Risk factors ; Index Medicus
    ISSN: 1080-6040
    E-ISSN: 1080-6059
    Source: Academic Search Ultimate
    Source: PubMed Central
    Library Location Call Number Volume/Issue/Year Availability
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  • 5
    Language: English
    In: Clinical cancer research, 2003, Vol.9 (7), p.2711-2718
    Description: The nuclear enzyme poly(ADP-ribose) polymerase (PARP-1) facilitates DNA repair, and is, therefore, an attractive target for anticancer chemo- and radio-potentiation. Novel benzimidazole-4-carboxamides (BZ1-6) and tricyclic lactam indoles (TI1-5) with PARP-1 K(i) values of 〈10 nM have been identified. Whole cell PARP-1 inhibition, intrinsic cell growth inhibition, and chemopotentiation of the cytotoxic agents temozolomide (TM) and topotecan (TP) were evaluated in LoVo human colon carcinoma cells. The acute toxicity of the inhibitors was investigated in PARP-1 null and wild-type mice. Tissue distribution and in vivo chemopotentiation activity was determined in nude mice bearing LoVo xenografts. At a nontoxic concentration (0.4 micro M) the PARP-1 inhibitors potentiated TM-induced growth inhibition 1.0-5.3-fold and TP-induced inhibition from 1.0-2.1-fold. Concentrations of the PARP-1 inhibitors that alone inhibited cell growth by 50% ranged from 8 to 94 micro M. Maximum potentiation of TM activity was achieved at nongrowth inhibitory concentrations (〈/=1 micro M) of potent PARP-1 inhibitors BZ5 and TI4. Whole cell PARP-1 inhibition by BZ3, BZ5, BZ6, TI1, and TI4 was confirmed by attenuation of DNA damage-induced NAD(+) depletion. Selected inhibitors (TI1, TI3, and TI4), in contrast to the benchmark compound PD128763, caused only mild hypothermia in both PARP-1 null and wild-type mice. Excellent distribution of BZ5, TI1, and TI3 into tumor tissue was observed, and TI3 enhanced TM antitumor activity in vivo. These studies have identified potent nontoxic PARP-1 inhibitors with structural modifications that promote aqueous solubility, tolerability, and tissue distribution. These compounds are important leads in the development of clinically viable PARP-1 inhibitors.
    Subject(s): Biological and medical sciences ; Chemotherapy ; Medical sciences ; Antineoplastic agents ; Pharmacology. Drug treatments ; Temperature ; Models, Chemical ; Dacarbazine - therapeutic use ; Humans ; Enzyme Inhibitors - pharmacology ; Topotecan - toxicity ; Antineoplastic Agents, Alkylating - pharmacology ; Topotecan - therapeutic use ; Poly(ADP-ribose) Polymerase Inhibitors ; Dose-Response Relationship, Drug ; Tissue Distribution ; Indoles - metabolism ; Poly(ADP-ribose) Polymerases - genetics ; Time Factors ; Cell Division ; DNA Repair ; Dacarbazine - analogs & derivatives ; Cell Line, Tumor ; Antineoplastic Agents - pharmacology ; Kinetics ; Dacarbazine - toxicity
    ISSN: 1078-0432
    E-ISSN: 1557-3265
    Source: HighWire Press (Free Journals)
    Source: Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
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