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  • 1
    Language: English
    In: Journal of demographic economics, 2021-03, Vol.87 (1), p.1-31
    Description: Pensions may be provided for in a modern society by a mix of several methods, namely by voluntary individual savings, mandatory fully-funded occupational pension systems, mandatory social security financed by pay-as-you-go, and old-fashioned hoarding in cash. We call a specific mixture of the four systems a pension composition. We assume that individual workers decide on their own individual savings, that the fully-funded occupational system is decided upon by the age cohort of the median worker (MW), and that social security is decided upon by the median voter (MV). We assume that individual and collective pension savings are the only sources of capital supply. When capital supply equals demand from industry there is equilibrium in the capital market with a corresponding equilibrium interest rate and pension composition. In this paper we assume a demography with one hundred age brackets and we investigate how changes in the birth rates, survival rates, and the retirement age affect the pension composition and the capital market equilibrium. Our conclusion is that for a given technology the pension composition and the interest rate are determined by the demography and cannot be modified at will as a long-term political instrument.
    ISSN: 2054-0892
    E-ISSN: 2054-0906
    Source: Alma/SFX Local Collection
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  • 2
    Language: English
    In: Journal of applied econometrics (Chichester, England), 1994-04, Vol.9 (2), p.133-161
    Description: In this paper a model for the labour market is developed which extends the traditional microeconomic studies of the labour market in two ways. First, the household is taken as the unit of observation and is considered to be the (potential) supplier of the labour of both husband and wife. The labour supply of the spouses is assumed to be jointly determined by characteristics of the household as well as individual characteristics. Second, following an earlier paper (Van Praag et al. (1991), where the female labour market is analysed separately, both the supply behaviour of the spouses and the labour demand behaviour of the employers is modelled. We apply an algorithm which needs only a few simulations per observation, while the simulation procedure generates drawings from the eight-dimensional intervals in an efficient way. Empirical results are presented for a sample of Dutch households in 1983. With the model the impact of policy measures on employment can be evaluated. It follows that a substantial part of participation can be attributed to the `insider-advantage' for employed individuals. Further it appears that the labour market for women is more sensitive to changes in the socio-economic environment than the labour market for men.
    Subject(s): Children ; Econometrics ; Economic models ; Economic theory ; Employment ; Households ; Labor market ; Labor markets ; Labor supply ; Labour market ; Men ; Minimum wage ; Studies ; Supply ; Unemployment ; Wage rate ; Wages
    ISSN: 0883-7252
    E-ISSN: 1099-1255
    Source: International Bibliography of the Social Sciences (IBSS)
    Source: JSTOR Arts & Sciences I
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  • 3
    Article
    Article
    1996
    ISSN: 0013-0583 
    Language: English
    In: Economisch-statistische Berichten, 1996, Vol.81, p.39-40
    ISSN: 0013-0583
    Source: Alma/SFX Local Collection
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  • 4
    Article
    Article
    1995
    ISSN: 0013-0583 
    Language: English
    In: Economisch-statistische Berichten, 1995, Vol.80, p.996-999
    Subject(s): class eco D
    ISSN: 0013-0583
    Source: Alma/SFX Local Collection
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  • 5
    Article
    Article
    2004
    ISSN: 0013-0583 
    Language: Dutch
    In: Economisch-statistische Berichten, 2004, Vol.89 (4438), p.344-346
    ISSN: 0013-0583
    Source: Alma/SFX Local Collection
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  • 6
    Article
    Article
    1996
    ISSN: 0013-0583 
    Language: Dutch
    In: Economisch-statistische Berichten, 1996-01-10, Vol.81, p.39
    ISSN: 0013-0583
    Source: Alma/SFX Local Collection
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  • 7
    Language: English
    In: Journal of clinical oncology, 2011-11-01, Vol.29 (31), p.4143-4150
    Description: PURPOSE: We studied cumulative incidence, risk factors, therapeutic strategies, and outcome of symptomatic osteonecrosis in pediatric patients with acute lymphoblastic leukemia (ALL). PATIENTS AND METHODS: Cumulative incidence of osteonecrosis was assessed prospectively in 694 patients treated with the dexamethasone-based Dutch Child Oncology Group-ALL9 protocol. Osteonecrosis was defined by development of symptoms (National Cancer Institute grade 2 to 4) during treatment or within 1 year after treatment discontinuation, confirmed by magnetic resonance imaging. We evaluated risk factors for osteonecrosis using logistic multivariate regression. To describe outcome, we reviewed clinical and radiologic information after antileukemic treatment 1 year or more after osteonecrosis diagnosis. RESULTS: Cumulative incidence of osteonecrosis at 3 years was 6.1%. After adjustment for treatment center, logistic multivariate regression identified age (odds ratio [OR], 1.47; P 〈 .01) and female sex (OR, 2.23; P = .04) as independent risk factors. Median age at diagnosis of ALL in patients with osteonecrosis was 13.5 years, compared with 4.7 years in those without. In 21 (55%) of 38 patients with osteonecrosis, chemotherapy was adjusted. Seven patients (18%) underwent surgery: five joint-preserving procedures and two total-hip arthroplasties. Clinical follow-up of 35 patients was evaluated; median follow-up was 4.9 years. In 14 patients (40%), symptoms completely resolved; 14 (40%) had symptoms interfering with function but not with activities of daily living (ADLs; grade 2); seven (20%) had symptoms interfering with ADLs (grade 3). In 24 patients, radiologic follow-up was available; in six (25%), lesions improved/disappeared; in 13 (54%), lesions remained stable; five (21%) had progressive lesions. CONCLUSION: Six percent of pediatric patients with ALL developed symptomatic osteonecrosis during or shortly after treatment. Older age and female sex were risk factors. After a median follow-up of 5 years, 60% of patients had persistent symptoms.
    Subject(s): Adolescent ; Age Factors ; Antineoplastic Combined Chemotherapy Protocols - administration & dosage ; Antineoplastic Combined Chemotherapy Protocols - adverse effects ; Biological and medical sciences ; Child ; Child, Preschool ; Dexamethasone - administration & dosage ; Dexamethasone - adverse effects ; Diseases of the osteoarticular system ; Female ; Follow-Up Studies ; Humans ; Incidence ; Kaplan-Meier Estimate ; Logistic Models ; Magnetic Resonance Imaging ; Male ; Medical sciences ; Multivariate Analysis ; Netherlands - epidemiology ; Odds Ratio ; Osteonecrosis - chemically induced ; Osteonecrosis - diagnosis ; Osteonecrosis - diagnostic imaging ; Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy ; Prevalence ; Proportional Hazards Models ; Prospective Studies ; Radiography ; Risk Assessment ; Risk Factors ; Sex Factors ; Time Factors ; Treatment Failure ; Treatment Outcome ; Tumors ; Vascular bone diseases
    ISSN: 0732-183X
    E-ISSN: 1527-7755
    Source: Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
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  • 8
    Language: English
    In: BJOG : an international journal of obstetrics and gynaecology, 2014, Vol.121 (8), p.1005-1014
    Description: To assess the effect of red blood cell (RBC) transfusion on quality of life in acutely anaemic women after postpartum haemorrhage. Randomised non-inferiority trial. Thirty-seven Dutch university and general hospitals. Women with acute anaemia (haemoglobin 4.8-7.9 g/dl [3.0-4.9 mmol/l] 12-24 hours postpartum) without severe anaemic symptoms or severe comorbidities. Women were allocated to RBC transfusion or non-intervention. Primary outcome was physical fatigue 3 days postpartum (Multidimensional Fatigue Inventory, scale 4-20; 20 represents maximal fatigue). Non-inferiority was demonstrated if the physical fatigue difference between study arms was maximal 1.3. Secondary outcomes were health-related quality of life and physical complications. Health-related quality of life questionnaires were completed at five time-points until 6 weeks postpartum. In all, 521 women were randomised to non-intervention (n = 262) or RBC transfusion (n = 259). Mean physical fatigue score at day 3 postpartum, adjusted for baseline and mode of delivery, was 0.8 lower in the RBC transfusion arm (95% confidence interval: 0.1-1.5, P = 0.02) and at 1 week postpartum was 1.06 lower (95% confidence interval: 0.3-1.8, P = 0.01). A median of two RBC units was transfused in the RBC transfusion arm. In the non-intervention arm, 33 women received RBC transfusion, mainly because of anaemic symptoms. Physical complications were comparable. Statistically, non-inferiority could not be demonstrated as the confidence interval crossed the non-inferiority boundary. Nevertheless, with only a small difference in physical fatigue and no differences in secondary outcomes, implementation of restrictive management seems clinically justified
    Subject(s): Abridged Index Medicus ; Adult ; Anaemia ; Anemia - etiology ; Anemia - therapy ; Blood transfusion ; Erythrocyte Transfusion - standards ; Fatigue - etiology ; Fatigue - therapy ; Female ; Follow-Up Studies ; Health aspects ; Hemoglobin ; Hospitals, General ; Hospitals, University ; Humans ; Maternal Welfare ; Netherlands ; postpartum haemorrhage ; Postpartum Hemorrhage - therapy ; Practice Guidelines as Topic ; Quality of Life ; Risk Assessment ; Severity of Illness Index ; Treatment Outcome
    ISSN: 1470-0328
    E-ISSN: 1471-0528
    Source: Wiley Online Library All Journals
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  • 9
    Language: English
    In: The Journal of hospital infection, 2002-08, Vol.51 (4), p.288-296
    Description: Invasive aspergillosis is the most prevalent mould infection. An epidemiological surveillance network was set up in 18 teaching hospitals in Paris and the Greater Paris area. Prospective surveillance was conducted between 1994 and 1999. Between 1994 and 1997 cases were categorized as proven or probable aspergillosis and then the European Organization for Research and Treatment of Cancer/Mycoses Study Group criteria were used. The authors analysed 621 cases (115 proven, 506 probable). No seasonal variation was found. Haematological disorders (73%) including stem-cell transplantation (36%), solid-organ transplantations (10%) and AIDS (9%) were the main underlying conditions. The crude mortality was 63%. Incidence of IA was 8% (CI95: 6.5–9.5) in acute myelocytic leukaemia and 6.3% (CI95: 4.3–8.3) in acute lymphocytic leukaemia. Incidence was 12.8% (CI95: 10.8–14.8) following allogeneic stem-cell transplantation and 1.1% (CI95: 0.7–1.5) following autologous stem-cell transplantation. In solid-organ recipients incidence ranged from 11% following heart–lung transplantation and small bowel to 0.4% following kidney transplantation. Incidence in HIV infected patients ranged from 0.02 to 0.13% per annum. This large series confirmed that patients with haematologic disorders and transplantations are the most at risk for IA.
    Subject(s): Adolescent ; Adult ; Aged ; Aged, 80 and over ; Aspergillosis - epidemiology ; Aspergillosis - etiology ; Aspergillosis - mortality ; Aspergillosis, epidemiology, immunodeficiency ; Biological and medical sciences ; Child ; Child, Preschool ; Cross Infection - epidemiology ; Cross Infection - etiology ; Cross Infection - mortality ; Female ; Hematologic Diseases - complications ; Hematopoietic Stem Cell Transplantation - adverse effects ; HIV Infections - complications ; Human mycoses ; Humans ; Immunocompromised Host ; Incidence ; Infant ; Infant, Newborn ; Infectious diseases ; Male ; Medical sciences ; Middle Aged ; Miscellaneous mycoses ; Mycoses ; Organ Transplantation - adverse effects ; Paris - epidemiology ; Prospective Studies ; Risk Factors ; Seasons ; Statistics, Nonparametric
    ISSN: 0195-6701
    E-ISSN: 1532-2939
    Source: Backfile Package - All of Back Files EBS [ALLOFBCKF]
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  • 10
    Language: English
    In: Fertility and sterility, 1995-07, Vol.64 (1), p.37-43
    Description: To study the relationship between decreasing serum FSH levels in the follicular phase of the normal menstrual cycle and follicle development by means of transvaginal sonography and E2 production. Daily blood samples were taken and transvaginal sonography was performed every other day in 16 normal regularly cycling female volunteers. Serum levels of FSH, LH, E2, and P and follicle diameter by transvaginal sonography. A distinct variability in individual maximal early follicular phase FSH plasma levels was observed (range 4.4 to 11.2 mIU/mL [conversion factor to SI unit, 1.000]). Differences in maximum FSH levels did not correlate with other endocrine or sonographic follicular phase characteristics. The follicular phase FSH decrease (from median 6.6 to 2.9 mIU/mL [conversion factor to SI unit, 1.000]) took place between cycle day 5 and 13 and was linear (0.5 ± 0.05 mIU/mL per day; mean ± SD). A significant correlation was found between serum FSH decrease and E2 increase. The day of sonographic appearance of a dominant follicle (median cycle day 8) did correlate with the first rise of the E2 plasma concentration. The present study suggests that even in women exhibiting normal ovarian function a 2.5-fold difference in FSH threshold concentrations for follicle recruitment does occur. Moreover, the magnitude of decrease in serum FSH concentrations during the follicular phase affects dominant follicle E2 production. The sonographic appearance of the dominant follicle is associated with a rise in serum E2 levels.
    Subject(s): Adult ; Biological and medical sciences ; Estradiol - blood ; Female ; follicle development ; follicle growth ; Follicle Stimulating Hormone - blood ; Follicular Phase ; FSH ; Fundamental and applied biological sciences. Psychology ; Hormone metabolism and regulation ; Humans ; Luteinizing Hormone - blood ; Mammalian female genital system ; menstrual cycle ; Osmolar Concentration ; Ovarian Follicle - diagnostic imaging ; Ovarian Follicle - physiology ; physiology ; Progesterone - blood ; transvaginal sonography ; Ultrasonography ; Vertebrates: reproduction
    ISSN: 0015-0282
    E-ISSN: 1556-5653
    Source: Alma/SFX Local Collection
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