placeholder
and
and

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Proceed order?

Export
Filter
Language
Year
  • 1
    Language: English
    In: BMJ (Clinical research ed.), 26 October 2017, Vol.359, pp.j4695
    Description:  To determine physician characteristics associated with exnovation (scaling back on use) and de-adoption (abandoning use) of carotid revascularization. Retrospective longitudinal cohort study. Medicare claims linked to the Doximity database provider registry, 2006-13. 9158 physicians who performed carotid revascularization on Medicare patients between 2006 and 2013. The primary outcomes were the number of carotid revascularization procedures for each physician per year at the end of the sample period, and the percentage change in the volume of carotid revascularization procedures. At baseline (2006-07), 9158 physicians performed carotid revascularization. By 2012-13 the use of revascularization in this cohort had declined by 37.7%, with two thirds attributable to scaling back (exnovation) rather than dropping the procedure entirely (de-adoption). Compared with physicians with fewer than 12 years of experience, those with more than 25 years of experience decreased use by an additional 23.0%...
    Subject(s): Practice Patterns, Physicians' ; Carotid Stenosis -- Surgery ; Endarterectomy, Carotid -- Statistics & Numerical Data
    ISSN: 0959-8138
    E-ISSN: 1756-1833
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Language: English
    In: JAMA : the journal of the American Medical Association, 11 July 2017, Vol.318(2), pp.128-130
    Description: A study by Yu and colleagues presenting the results of a meta-analysis of RCTs evaluating the relationship of PAP treatment for sleep apnea with major adverse cardiovascular events (including a composite of acute coronary syndrome events, stroke, or vascular death) and mortality is discussed. Yu et al concluded that PAP compared with no treatment or sham PAP was not associated with reduced risks of cardiovascular outcomes or death for patients with sleep apnea, the point estimate from the meta-analysis suggests the possibility of potential benefits as great as those of antithrombotic, lipid-lowering, or 13-blocker therapy. Yu added that, far from discouraging further research efforts, the analysis should serve as an impetus for additional studies that will allow the question, "Does OSA treatment reduce vascular disease risk?" to be properly answered. Despite the complexity of OSA treatment trials, the rationale for conducting these trials remains strong.
    Subject(s): Medicine
    ISSN: 0098-7484
    E-ISSN: 1538-3598
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    In: American Journal of Primatology, April 2013, Vol.75(4), pp.314-323
    Description: The human intruder test is a testing paradigm designed to measure rhesus macaques’ behavioral responses to a stressful and threatening situation. In the test, an unfamiliar human positions him/herself in various threatening positions relative to a caged macaque. This paradigm has been utilized for over 20 years to measure a variety of behavioral constructs, including fear and anxiety, behavioral inhibition, emotionality, and aggression. To date, there have been no attempts to evaluate comprehensively the structure of the behavioral responses to the test. Our first goal was to identify the underlying latent factors affecting the different responses among subjects, and our second goal was to determine if rhesus reared in different environments respond differently in this testing paradigm. To accomplish this, we first performed exploratory and confirmatory factor analyses on the behavioral responses of 3‐ to 4‐month‐old rhesus macaques, utilizing data from over 2,000 separate tests conducted between 2001–2007. Using the resulting model, we then tested to see whether early rearing experience affected responses in the test. Our first analyses suggested that most of the variation in infant behavioral responses to the human intruder test could be explained by four latent factors: “activity,” “emotionality,” “aggression,” and “displacement.” Our second analyses revealed a significant effect of rearing condition for each factor score ( 〈 0.001); most notable socially reared animals had the lowest activity score ( 〈 0.001), indoor mother‐reared animals had the highest displacement score ( 〈 0.001), and nursery‐reared animals had the highest emotionality ( 〈 0.001) and lowest aggression scores ( 〈 0.001). These results demonstrate that this standardized testing paradigm reveals multiple patterns of response, which are influenced by an animal's rearing history. Am. J. Primatol. 75:314‐323, 2013. © 2012 Wiley Periodicals, Inc.
    Subject(s): Human Intruder Test ; Emotionality ; Confirmatory Factor Analysis ; Rhesus Monkeys ; Macaca Mulatta
    ISSN: 0275-2565
    E-ISSN: 1098-2345
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Article
    Article
    2017
    ISSN: 0012-9682 
    In: Econometrica, January 2017, Vol.85(1), pp.67-105
    Description: This paper proposes a perfectly competitive model of a market with adverse selection. Prices are determined by zero‐profit conditions, and the set of traded contracts is determined by free entry. Crucially for applications, contract characteristics are endogenously determined, consumers may have multiple dimensions of private information, and an equilibrium always exists. Equilibrium corresponds to the limit of a differentiated products Bertrand game. We apply the model to establish theoretical results on the equilibrium effects of mandates. Mandates can increase efficiency but have unintended consequences. With adverse selection, an insurance mandate reduces the price of low‐coverage policies, which necessarily has indirect effects such as increasing adverse selection on the intensive margin and causing some consumers to purchase less coverage.
    Subject(s): Adverse Selection ; Contract Theory ; General Equilibrium
    ISSN: 0012-9682
    E-ISSN: 1468-0262
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    In: American Journal of Primatology, October 2013, Vol.75(10), pp.995-1008
    Description: Captive rhesus macaques sometimes exhibit undesirable abnormal behaviors, such as motor stereotypic behavior (MSB) and self-abuse. Many risk factors for these behaviors have been identified but the list is far from comprehensive, and large individual differences in rate of behavior expression remain. The goal of the current study was to determine which experiences predict expression of MSB and self-biting, and if individual differences in personality can account for additional variation in MSB expression. A risk factor analysis was performed utilizing data from over 4,000 rhesus monkeys at the California National Primate Research Center. Data were analyzed using model selection, with the best fitting models evaluated using Akaike Information Criterion. Results confirmed previous research that males exhibit more MSB and self-biting than females, MSB decreases with age, and indoor reared animals exhibit more MSB and self-biting than outdoor reared animals. Additionally, results indicated that animals exhibited less MSB and self-biting for each year spent outdoors; frequency of room moves and number of projects positively predicted MSB; pair separations positively predicted MSB and self-biting; pair housed animals expressed less MSB than single housed and grate paired animals; and that animals expressed more MSB and self-biting when in bottom rack cages, or cages near the room entrance. Based on these results we recommend limiting exposure to these risk factors when possible. Our results also demonstrated a relationship between personality and MSB expression, with animals low on gentle temperament, active in response to a human intruder, and high on novel object contact expressing more MSB. From these results we propose that an animal's MSB is related to its predisposition for an active personality, with active animals expressing higher rates of MSB. Am. J. Primatol. 75:995-1008, 2013. © 2013 Wiley Periodicals, Inc. Copyright John Wiley & Sons. Reproduced with permission. An electronic version of this article is available online at http://www.interscience.wiley.com
    Subject(s): Stereotypy ; Self‐Abuse ; Personality ; Rhesus ; Risk‐Factor ; Management
    ISSN: 0275-2565
    E-ISSN: 1098-2345
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    In: Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences, 2011, Vol. 66A(11), pp.1251-1257
    Description: Background. Resistance training programs have been found to improve muscle strength, physical function, and depressive symptoms in middle-aged and older adults. These programs have typically been provided in clinical facilities, health clubs, and senior centers, which may be inconvenient and/or cost prohibitive for some older adults. The purpose of this study was to investigate the effectiveness of an automated telemedicine intervention that provides real-time guidance and monitoring of resistance training in the home. Methods. A randomized clinical trial in 103 middle-aged or older participants. Participants were assigned to use of a theory-driven interactive voice response system designed to promote resistance training (Telephone-Linked Computer-based Long-term Interactive Fitness Trainer; n = 52) or to an attention control (n = 51) for a period of 12 months. Measurements of muscle strength, balance, walk distance, and mood were obtained at baseline, 3, 6, and 12 months. Results. We observed increased strength, improved balance, and fewer depressive symptoms in the intervention group than in the control group. Using generalized estimating equations modeling, group differences were statistically significant for knee flexion strength (p = .035), single-leg stance time (p = .029), and Beck Depression Inventory (p = .030). Conclusions. This computer-based telecommunications exercise intervention led to improvements in participants' strength, balance, and depressive symptoms. Because of their low cost and easy accessibility, computer-based interventions may be a cost-effective way of promoting exercise in the home. Key Words: Muscle strength--Balance--Resistance training. doi: 10.1093/gerona/glr138
    Subject(s): Muscle Strength ; Balance ; Resistance Training
    ISSN: 1079-5006
    E-ISSN: 1758-535X
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    In: International Social Security Review, July 2015, Vol.68(3), pp.69-98
    Description: In this article the adequacy of social insurance benefits is addressed from the perspective of eight fundamental goals of social insurance. With respect to these goals, the legislated level of the benefit and other conditions represent tools to achieve adequate levels of benefits vis‐à‐vis contributory effort. The goals address income risks of various sorts: (i) income compensation; (ii) securing a decent standard of living; (iii) universality, implying simplicity and a high takeup of social rights; (iv) reducing income risk deriving from physical incapacity; (v) safeguarding insurability by balancing the expected payoff to the insured and the value of the contributions paid over the lifetime; (vi) intergenerational equity; (vii) containing work and savings disincentives; and (viii) risk reduction (prevention). A simple model serves to clarify what is needed to achieve benefit adequacy together with insurability and contribution adequacy. An example of income support in working age, based on Israeli data, illustrates the use of specific instruments to achieve a decent standard of living while containing economic disincentives. The example stresses the importance of synchronizing efforts with institutions outside the social insurance system.
    Subject(s): Social Insurance ; Adequacy ; Benefits ; Contributions ; Insured Persons Rights ; Standard Of Living ; Israel ; Assurance Sociale ; Adéquation ; Prestations ; Cotisations ; Droit Des Assurés ; Niveau De Vie ; Israël ; Seguro Social ; Adecuación ; Prestaciones ; Cotizaciones ; Derechos De Los Asegurados ; Nivel De Vida ; Israel ; Sozialversicherung ; Angemessenheit ; Leistungen ; Beiträge ; Rechte Der Versicherten ; Lebensstandard ; Israel
    ISSN: 0020-871X
    E-ISSN: 1468-246X
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    In: American Journal of Primatology, September 2018, Vol.80(9), pp.n/a-n/a
    Description: Healthy rhesus macaque infant growth is 4.0–4.7 g/day throughout the first year of life. Diarrhea is associated with 11–34% decreased weight gain in the first year of life.
    Subject(s): Diarrhea ; Growth Standard ; Morphometrics ; Non‐Human Primates ; Stunting
    ISSN: 0275-2565
    E-ISSN: 1098-2345
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    In: Circulation, 2011, Vol.123(12), pp.1280-1286
    Description: BACKGROUND—: Prospective data suggest that sleep-disordered breathing enhances risk for incident and recurrent cardiovascular disease (CVD). However, a reverse causal pathway whereby incident CVD causes or worsens sleep-disordered breathing has not been studied. METHODS AND RESULTS—: A total of 2721 Sleep Heart Health Study participants (mean age 62, standard deviation=10 years; 57% women; 23% minority) without CVD at baseline underwent 2 polysomnograms 5 years apart. Incident CVD events, including myocardial infarction, congestive heart failure, and stroke, were ascertained and adjudicated. The relation of incident CVD to change in apnea-hypopnea index between the 2 polysomnograms was tested with general linear models, with adjustment for age, sex, race, study center, history of diabetes mellitus, change in body mass index, change in neck circumference, percent sleep time spent in supine sleep, and time between the 2 polysomnograms. Incident CVD occurred in 95 participants between the first and second polysomnograms. Compared with participants without incident CVD, those with incident CVD experienced larger increases in apnea-hypopnea index between polysomnograms. The difference in adjusted mean apnea-hypopnea index change between subjects with and without incident CVD was 2.75 events per hour (95% confidence interval, 0.26 to 5.24; P=0.032). This association persisted after subjects with central sleep apnea were excluded. Compared with participants without incident CVD, participants with incident CVD had greater increases in both mean obstructive and central apnea indices, by 1.75 events per hour (95% confidence interval, 0.10 to 1.75; P=0.04) and by 1.07 events per hour (95% confidence interval, 0.40 to 1.74; P=0.001), respectively. CONCLUSIONS—: In a diverse, community-based sample of middle-aged and older adults, incident CVD was associated with worsening sleep-disordered breathing over 5 years.
    Subject(s): Medicine ; Anatomy & Physiology;
    ISSN: 0009-7322
    E-ISSN: 15244539
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Language: English
    In: Journal of the American College of Cardiology, 23 October 2012, Vol.60(17), pp.B46-B46
    Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jacc.2012.08.179 Byline: Steven Burke, Emma Moss, Karen Macdonald, Marco Wong, Daniel Gottlieb, Kimberly Bland, F. Nicholas Franano Author Affiliation: (1) Proteon Therapeutics, Inc., Waltham, MA (2) Biopta Ltd, Glasgow, Glasgow (3) Proteon Therapeutics, Kansas City, MO (4) Proteon Therapeutics, Waltham, MA (5) Novita Therapeutics, LLC, Kansas City, MO
    Subject(s): Medicine
    ISSN: 0735-1097
    E-ISSN: 1558-3597
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...